2-Amino-6-methoxybenzothiazole Chemical Properties

Melting point:

165-167 °C (lit.)

Boiling point:

240°C

Density 

1.2425 (rough estimate)

refractive index 

1.5690 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

very slightly in Methanol

pka

pK1: 4.50(+1) (25°C)

form 

Crystalline Powder

color 

White to beige

Water Solubility 

<0.1 g/100 mL at 21 ºC

Stability:

Stable, but may be light sensitive. Incompatible with strong oxidizing agents.

CAS DataBase Reference

1747-60-0(CAS DataBase Reference)

EPA Substance Registry System

2-Amino-6-methoxybenzothiazole (1747-60-0)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38-20/21/22

Safety Statements 

26-36

RIDADR 

2811

WGK Germany 

3

RTECS 

DL2100000

TSCA 

Yes

HazardClass 

IRRITANT

PackingGroup 

III

HS Code 

29342080

Toxicity

mouse,LD50,intravenous,140mg/kg (140mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 486, 1952.

MSDS

• Language:English Provider:6-Methoxy-2-aminobenzothiazole
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Amino-6-methoxybenzothiazole Usage And Synthesis

Uses

2-Amino-6-methoxybenzothiazole is an intermediate used to prepare novel series of Schiff bases and 4-thiazolidinones. It is also used in the synthesis of 2-cyano-6-methoxybenzothiazole.

Chemical Properties

off-white to tan-coloured powder

Uses

2-Amino-6-methoxybenzothiazole was used as building block in the syntheses of novel series of Schiff bases and 4-thiazolidinones. It was used in the synthesis of 2-cyano-6-methoxybenzothiazole, key intermediate for the synthesis of firefly luciferin.

General Description

Fine off-white to light tan powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Amino-6-methoxybenzothiazole may be sensitive to exposure to light. 2-Amino-6-methoxybenzothiazole is incompatible with strong oxidizers.

Fire Hazard

Flash point data for 2-Amino-6-methoxybenzothiazole are not available; however, 2-Amino-6-methoxybenzothiazole is probably combustible.

2-Amino-6-methoxybenzothiazole(1747-60-0)Related Product Information

• Guaiacol
• Benzothiazole
• 2,2'-Dithiobis(benzothiazole)
• p-Anisaldehyde
• 4-Methoxyphenol
• 3-Aminophenol
• 2-Benzothiazolamine
• (Trifluoromethoxy)benzene
• Glycine
• ALTRENOGEST
• 2-Aminothiazole
• Anisole
• 6-Aminocaproic acid
• 2-Mercaptobenzothiazole
• Tris(hydroxymethyl)aminomethane
• 2-Amino-6-ethoxybenzothiazole
• 2-ACETOACETAMIDO-6-ETHOXYBENZOTHIAZOLE
• Basic Blue 54