Deracoxib
Deracoxib Basic information
- Product Name:
- Deracoxib
- Synonyms:
-
- Benzenesulfonamide, 4-3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl-
- 4-(3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl)benzenesulfonamide
- Deracoxib [usan]
- Deramaxx
- Sc 46
- Sc 59046
- Unii-vx29jb5xwv
- 4-[5-(3-Fluoro-4-Methoxyphenyl)-3-(difluoroMethyl)-1H-pyrazol-1-yl]benzenesulfonaMide
- CAS:
- 169590-41-4
- MF:
- C17H14F3N3O3S
- MW:
- 397.37
- EINECS:
- 807-307-6
- Product Categories:
-
- 169590-41-4
- Mol File:
- 169590-41-4.mol
Deracoxib Chemical Properties
- Melting point:
- 159-161°
- Boiling point:
- 575.5±60.0 °C(Predicted)
- Density
- 1.48
- storage temp.
- 2-8°C
- solubility
- Acetonitrile (Slightly), DMSO (Slightly)
- pka
- 9.69±0.10(Predicted)
- form
- Solid
- color
- Light Brown
Deracoxib Usage And Synthesis
Uses
Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatment of osteoarthritis in dogs. At low doses, adminsitartion of Deracoxin showed no factors associated with gastrointestinal tract perforation.
Definition
ChEBI: A member of the class of pyrazoles that is 1H-pyrazole which is substituted at positions 1, 3, and 5 by 4-sulfamoylphenyl, difluoromethyl and 3-fluoro-4-methoxyphenyl groups, respectively. A selective cyclooxygenase 2 inhibitor, it is us d in veterinary medicine for the control of pain and inflammation associated with osteoarthritis in dogs.
Veterinary Drugs and Treatments
Deracoxib is indicated for the treatment of post-operative pain
(higher dose, 7 day maximum), and for the treatment of pain and
inflammation associated with osteoarthritis (lower dose, ongoing
dosing) in dogs.
Like piroxicam, deracoxib is of interest in adjunctive treatment
of transitional cell carcinoma of the bladder; investigations into this
use are ongoing.
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