(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic
(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic Basic information
- Product Name:
- (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic
- Synonyms:
-
- (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic
- UDP-D-glucuronic acid
- UDP-glucuronic acid
- Uridine 5'-(trihydrogen diphosphate)mono-α-D-glucopyranuronosyl
- Uridine diphosphoglucuronic acid
- Uridine pyrophosphoglucuronic acid
- UDP-alpha-D-glucuronic acid
- Uridine diphosphate glucuronic acid
- CAS:
- 2616-64-0
- MF:
- C15H22N2O18P2
- MW:
- 580.28
- Mol File:
- 2616-64-0.mol
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(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic Chemical Properties
- Density
- 2.05±0.1 g/cm3(Predicted)
- pka
- 1.10±0.50(Predicted)
- CAS DataBase Reference
- 2616-64-0
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(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic Usage And Synthesis
Description
An intermediate in the phase II reaction that results in the formation of glucuro_x0002_nic acid conjugates of xenobiotics which contain substituents such as hydroxyl, amino, or sulfhydryl groups, forming the O-, N-, and S-glucuronides, respectively. UDPGA is formed by two reactions: (i) the formation of UDPG from UTP and glucose 1-phosphate and (ii) the formation of UDPGA from UDPG. The two reactions are catalyzed by UDPG pyrophosphorylase and UDPG dehydrogenase, respectively, whereas glucuronide formation is catalyzed by glucuronosyltransferase. Glucuronide formation from xenobiotics is common in all animal groups except insects.
Definition
ChEBI: A UDP-sugar having alpha-D-glucuronic acid as the sugar component.
(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylicSupplier
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(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic(2616-64-0)Related Product Information
- UDP-a-D-Xylose disodium
- UDP-a-N-acetyl-D-galactosamine (ammonium salt)
- UDP-b-L-arabinopyranose disodium salt
- UDP-D-galactose
- UDPGA TRISODIUM SALT
- UDP-a-D-glucose (ammonium salt)
- Uridine 5'-diphosphoglucose disodium salt
- UDP-b-L-glucose (ammonium salt)
- UDP-a-D-galactose ammonium salt
- [5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[hydroxy-(3,4,5-trihydroxyoxan-2-yl)oxy-phosphoryl]oxy-phosphinic acid
- D-Glucuronic acid
- α-L-Rhamnopyranose monohydrate
- L-Arabinose
- L-Arabinopyranose
- D-Glucaric acid
- L(+)-Rhamnose monohydrate
- D-Galactose
- Uridine 5'-(trihydrogen diphosphate), mono-alpha-d-glucopyranosyl ester