Basic information Safety Supplier Related

UDP-D-galactose

Basic information Safety Supplier Related

UDP-D-galactose Basic information

Product Name:
UDP-D-galactose
Synonyms:
  • UDPG DISODIUM SALT
  • UDP-GAL
  • UDP-GALACTOSE DISODIUM SALT
  • UDP-GAL DISODIUM SALT
  • UDP-GAL, NA2
  • UDP-GALNAC, NA2
  • [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
  • UDP-galactopyranose
CAS:
2956-16-3
MF:
C15H24N2O17P2
MW:
566.3
Mol File:
2956-16-3.mol
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UDP-D-galactose Chemical Properties

Density 
1.97±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: 50 mg/mL, clear, colorless
pka
1.10±0.50(Predicted)
InChIKey
HSCJRCZFDFQWRP-ABVWGUQPSA-N
SMILES
O[C@@H]1[C@@H]([C@H](O[C@H]1N1C=CC(NC1=O)=O)COP(O)(=O)OP(O)(=O)O[C@@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO)O)O)O)O
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
10-21

MSDS

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UDP-D-galactose Usage And Synthesis

Uses

UDP-Galactose is a monosaccharide involved in nucleotide sugar metabolism. UDP-Galactose and its derivatives act as a natural agonist for Gi protein-conjugated P2Y14 receptors in the immune system (IC50=0.67 μM, hP2Y14)[1].

Definition

ChEBI: UDP-alpha-D-galactose is a UDP-D-galactose in which the anomeric centre of the galactose moiety has alpha-configuration. It has a role as a mouse metabolite. It is a conjugate acid of an UDP-alpha-D-galactose(2-).

IC 50

Human Endogenous Metabolite; P2Y14 Receptor: 0.67 μM (EC50)

References

[1] Ko H, et al. Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J Med Chem. 2007 May 3;50(9):2030-9. DOI:10.1021/jm061222w

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