Basic information Safety Supplier Related

Sodium levothyroxine pentahydrate

Basic information Safety Supplier Related

Sodium levothyroxine pentahydrate Basic information

Product Name:
Sodium levothyroxine pentahydrate
Synonyms:
  • 3-[4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]-L-ALANINE SODIUM SALT PENTAHYDRATE
  • 3-[4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]-L-ALANINE PENTAHYDRATE
  • 3,3',5,5'-TETRAIODO-L-THYRONINE SODIUM SALT PENTAHYDRATE
  • (S)-2-AMINO-3-[4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]PROPIONIC ACID SODIUM SALT PENTAHYDRATE
  • SODIUM (S)-2-AMINO-3-[4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]PROPIONATE PENTAHYDRATE
  • SODIUM LEVOTHYROXINE PENTAHYDRATE
  • 3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-alaninmonosodiumsa
  • lt,pentahydrate,
CAS:
6106-07-6
MF:
C15H20I4NNaO9
MW:
888.93
EINECS:
682-494-3
Product Categories:
  • Hormones
Mol File:
6106-07-6.mol
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Sodium levothyroxine pentahydrate Chemical Properties

Melting point:
207-210 (dec.)(lit.)
alpha 
[α]D20 +15~+19°
Density 
2.381
storage temp. 
2-8°C
solubility 
cell culture medium: 0.1 mg/mL
form 
powder
color 
White to Yellow to Orange
BRN 
5721845
CAS DataBase Reference
6106-07-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
40
Safety Statements 
22-24/25-36
WGK Germany 
3
RTECS 
YP2833760
3-8-10

MSDS

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Sodium levothyroxine pentahydrate Usage And Synthesis

Hazard

A reproductive hazard.

Biochem/physiol Actions

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Purification Methods

Crystallise the sodium salt from absolute EtOH and dry it for 8hours at 30o/1mm. [Canepa Acta Cryst 4 283 1951, Beilstein 14 II 378, 14 III 1566, 14 IV 2374.]

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