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Sodium levothyroxine

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Sodium levothyroxine Basic information

Product Name:
Sodium levothyroxine
Synonyms:
  • SODIUM LEVOTHYROXINE
  • SODIUM LEVOTHYROXINE, HYDRATE
  • sodium (2s)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoate
  • 3-[4-4-HYDROXY-3,5-DIIODOPHENOXY-3,5-DIIODOPHENYL]-L-ALANINE, HYDRATE
  • L-THYROXINE SODIUM SALT
  • L-THYROXINE SODIUM SALT, HYDRATE
  • L-THYROXINE SODIUM, HYDRATE
  • L-THYROXIN SODIUM
CAS:
25416-65-3
MF:
C15H10I4NNaO4
MW:
798.85
EINECS:
685-634-1
Product Categories:
  • Hormone Drugs
  • 25416-65-3
Mol File:
25416-65-3.mol
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Sodium levothyroxine Chemical Properties

Melting point:
207 °C
alpha 
16 º (c=2,1M HCl/alcohol 1/4)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Very slightly soluble in water, slightly soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides.
form 
Liquid
color 
Clear yellow to yellow-greenish
Water Solubility 
0.15 g/L (25 ºC)
Stability:
Hygroscopic
CAS DataBase Reference
25416-65-3(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29379000
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Sodium levothyroxine Usage And Synthesis

Uses

L-Thyroxine sodium hydrate is a useful research chemical. Its free form Thyroxine (T425600) is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.

Chemical Properties

almost white to beige or

Uses

Thyroid hormone replacement.

Definition

ChEBI: Levothyroxine sodium hydrate is an organic molecular entity.

brand name

Levo-T (Alara); Levolet (Vintage); Levothroid (Lloyd); Levoxyl (Jones); Novothyrox (Genpharm); Synthroid (Abbott); Unithroid (Stevens J).

Sodium levothyroxine Preparation Products And Raw materials

Preparation Products

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