ANTI-CYCLIN D2
ANTI-CYCLIN D2 Basic information
- Product Name:
- ANTI-CYCLIN D2
- Synonyms:
-
- ANTI-CYCLIN D2, NEUTRALIZING ANTIBODY
- Monoclonal Anti-Cyclin D2 antibody produced in mouse
- Monoclonal Anti-CCND2 antibody produced in mouse
- Anti-CCND2 antibody produced in rabbit
- Anti-CCND2 (127-139) antibody produced in rabbit
- Anti-CCND2 (261-275) antibody produced in rabbit
- ANTI-CYCLIN D2 (AB-1), HUMAN AND MOUSE
- ANTI-CYCLIN D2
- MW:
- 0
- Product Categories:
-
- Alphabetical Index
- Antibodies for Cell Cycle
- Antibodies to Cyclins and CDKsAntibodies
- Antibodies to CyclinsCell Biology
- Clone Index
- CO-CZAntibodies
- DCancer Research
- Hematopoietic Stem Cell Biology
- Hematopoietic Stem Cell Characterization/Differentiation
- Oncoproteins
- Tumor Growth Regulation
- Mol File:
- Mol File
ANTI-CYCLIN D2 Chemical Properties
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- rabbit
MSDS
- Language:English Provider:SigmaAldrich
ANTI-CYCLIN D2 Usage And Synthesis
Uses
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. (provided by RefSeq)