Basic information Safety Supplier Related

ascamycin

Basic information Safety Supplier Related

ascamycin Basic information

Product Name:
ascamycin
Synonyms:
  • ascamycin
  • (+)-5'-O-[[(S)-2-Amino-1-oxopropyl]aminosulfonyl]-2-chloroadenosine
  • 2-Chloro-5'-O-[(L-alanylamino)sulfonyl]adenosine
  • 2-Chloro-5'-O-[[(S)-2-amino-1-oxopropyl]sulfamoyl]adenosine
CAS:
91432-48-3
MW:
0
Mol File:
91432-48-3.mol
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ascamycin Usage And Synthesis

Biological Activity

Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. It has selective antibacterial activity against Xanthomonas bacteria, with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei, respectively.

in vitro

The Ascamycin has C2-chloroadenine as the base on C-1' which lacks the chlorine. Ascamycin has a selective antibacterial activity against Xanthomonas species. When Ascamycin is dealanylated, Dealanylascamycin shows a broad antibacterial activity against various Gram-negative and Gram-positive bacteria. Xanthomonas citri is susceptible to Ascamycin by virtue of the Ascamycin-dealanylating enzyme on the cell surface.

target

MIC: 0.4 μg/mL ( Xanthomonas citri ), 12.5 μg/mL ( Xanthomonas oryzae ) and 12.5 μg/mL ( Mycobacterium phlei )

ascamycinSupplier

TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
NewCan Biotech Limited
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+86-0571-86912261 +8613735419629
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sales@newcanbio.com
BOC Sciences
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16314854226; +16314854226
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inquiry@bocsci.com
Zhejiang Huida Biotech Co., LTD
Tel
0571-89903882 13626641628
Email
jiangnan@huidabiotech.com
Zhejiang Huida Biotech Co., LTD
Tel
0571-0571-89903882 15990081639
Email
sunshixuan@huidabiotech.com
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