2-Chloroadenosine hemidydrate Chemical Properties

Melting point:

160 °C (dec.)(lit.)

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

form 

powder

CAS DataBase Reference

81012-94-4

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

Safety Statements 

36

WGK Germany 

3

Hazard Note 

Harmful

HS Code 

2934999090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

2-Chloroadenosine hemidydrate Usage And Synthesis

Uses

2-Chloroadenosine can effectively inhibit the expression of tumor metastasis-related genes mtal and mRNA, and has inhibitory effects on various cancer cells. For example, it inhibits the in vitro invasion of highly metastatic human ovarian cancer cells HO-8910PM and the growth of human prostate cancer cells. 2-Chloroadenosine can also significantly increase spinal cord blood flow after injury, thereby improving post-injury neurological function. Furthermore, it is an important pharmaceutical intermediate; it can be used as a raw material to synthesize the anti-leukemia drug cladribine (2-chlorodeoxyadenosine).

Chemical Properties

white crystalline powder

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