TAUROCHOLIC ACID CAS#: 81-24-3

TAUROCHOLIC ACID Basic information

Product Name:

TAUROCHOLIC ACID

Synonyms:

TAUROCHOLIC ACID
2-((3-alpha,7-alpha,12-alpha-trihydroxy-24-oxo-5-beta-cholan-24-yl)amino)ethan
3,7,12-Trihydroxy-5-cholan-24-oicacid24-taurineamide
5-BETA-CHOLANIC ACID-3-ALPHA, 7-ALPHA, 12-ALPHA-TRIOL N-(2-SULPHOETHYL)-AMIDE
n-choloyltaurine
-oxocholan-24-yl]amino]-
taurocholate
2-[[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]ethanesulphonic acid

CAS:

81-24-3

MF:

C26H45NO7S

MW:

515.7

EINECS:

201-336-2

Product Categories:

Miscellaneous Natural Products
81-24-3

Mol File:

81-24-3.mol

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TAUROCHOLIC ACID Chemical Properties

Melting point:: 125°C (rough estimate)
alpha: D18 +38.8° (c = 2 in alcohol)
Density: 1.0902 (rough estimate)
refractive index: 1.5650 (estimate)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Ethanol (Slightly), Methanol (Slightly)
pka: 1.4(at 25℃)
form: Solid
color: White to Off-White
Stability:: Hygroscopic
LogP: 0.247 (est)
EPA Substance Registry System: Ethanesulfonic acid, 2-[[(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]- (81-24-3)

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Safety Information

Hazardous Substances Data: 81-24-3(Hazardous Substances Data)
Toxicity: LD50 in newborn rats: 380 mg/kg (Klaassen)

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TAUROCHOLIC ACID Usage And Synthesis

Chemical Properties

Crystals. Stable in air. Freely soluble in water; soluble in alcohol, almost insoluble in ether and ethyl acetate.

Uses

Taurocholic Acid is a choleretic steroid useful for the quantification of conjugated bile acids.

Uses

anti-inflammatory

Definition

ChEBI: A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.

Purification Methods

Crystallise the acid from EtOH/EtOAc/Et2O (amorphous m 125o) or EtOH/Et2O [Josephson Biochem J 29 1484 1935]. The sodium salt (hydrate) [312693-83-7, 345909-26-4 (xH2O)] crystallises from aqueous EtOH/Et2O with m 231-232o, [] D 23 +25.2o (c 1, H2O); and has max (H2SO4) at 303, 389 and 480nm. [Beilstein 10 III 2177, 10 IV 2078.]

TAUROCHOLIC ACID Preparation Products And Raw materials

Preparation Products

Dehydrocholic acid

TAUROCHOLIC ACIDSupplier

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Email: y.liu@mail.biobiopha.com

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Email: info@tsbiochem.com

Conier Chem & Pharma Co.,Ltd,

Tel: 023-62879767 13996269627;
Email: sales@conier.com

Shanghai Hekang Biotechnology Co., Ltd.

Tel: 18939837085
Email: youchemicals@gmail.com

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Email: sales@chem-strong.com

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