N,N-dimethyldoxorubicin
N,N-dimethyldoxorubicin Basic information
- Product Name:
- N,N-dimethyldoxorubicin
- Synonyms:
-
- N,N-dimethyldoxorubicin
- 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-
- CAS:
- 70222-95-6
- MF:
- C29H33NO11
- MW:
- 571.57
- Mol File:
- Mol File
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N,N-dimethyldoxorubicin Chemical Properties
- Boiling point:
- 801.1±65.0 °C(Predicted)
- Density
- 1.53±0.1 g/cm3(Predicted)
- pka
- 7.35±0.60(Predicted)
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N,N-dimethyldoxorubicin Usage And Synthesis
Uses
N,N-Dimethyldoxorubicin is a Doxorubicin (HY-15142A) analogue. N,N-Dimethyldoxorubicin shows cytotoxicity against a panel of tumor cell lines (IC50s < 0.3 μM)[1].
References
[1] Wander DPA, et al. Synthetic (N,N-Dimethyl)doxorubicin Glycosyl Diastereomers to Dissect Modes of Action of Anthracycline Anticancer Drugs. J Org Chem. 2021 Apr 16;86(8):5757-5770. DOI:10.1021/acs.joc.1c00220
N,N-dimethyldoxorubicinSupplier
Dalian Meilun Biotech Co., Ltd.
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Shanghai Lollane Biological Technology Co.,Ltd.
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TargetMol Chemicals Inc.
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Shanghai Qianhao Biotechnology Co., LTD
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