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XANTHOHUMOL

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XANTHOHUMOL Basic information

Product Name:
XANTHOHUMOL
Synonyms:
  • 2-Propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-
  • 1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)- 2-propen-1-one
  • Xanthohumol1
  • 1[2,4Dihydroxy6methoxy3(3methyl2buten1yl)phenyl]3(4hydroxyphenyl)2propen1one,1 [2,4 Dihydroxy 6 methoxy 3 (3 methyl 2 buten 1 yl)phenyl] 3 (4 hydroxyphenyl) 2 propen 1 one
  • (E/Z)-Xanthohumol
CAS:
569-83-5
MF:
C21H22O5
MW:
354.4
Product Categories:
  • Chalcones
Mol File:
569-83-5.mol
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XANTHOHUMOL Chemical Properties

Boiling point:
576.5±50.0 °C(Predicted)
Density 
1.244±0.06 g/cm3(Predicted)
solubility 
Soluble to 100 mM in DMSO and to 100 mM in ethanol
form 
powder
pka
7.47±0.45(Predicted)
color 
Yellow
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XANTHOHUMOL Usage And Synthesis

Definition

ChEBI: Xanthohumol is a member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells. It has a role as a metabolite, an apoptosis inducer, an antineoplastic agent, an antiviral agent, an EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor and an anti-HIV-1 agent. It is a member of chalcones, a polyphenol and an aromatic ether. It is a conjugate acid of a xanthohumol(1-).

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