Basic information Safety Supplier Related

AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT

Basic information Safety Supplier Related

AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Basic information

Product Name:
AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
Synonyms:
  • H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (DISULFIDE BRIDGE: 3-14), ACETATE SALT
  • AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
  • SOMATOSTATIN 14, ACETATE
  • Somatostatin monoacetate
  • GHIH
  • Somatostatin (sheep), monoacetate (salt)
  • Somatostatin-14 (human, mouse, rat, porcine, bovine, ovine) (acetate)
  • Cyclic somatostatin Acetate
CAS:
54472-66-1
MF:
C78H108N18O21S2
MW:
1697.95
Product Categories:
  • peptide
Mol File:
Mol File
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AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Chemical Properties

storage temp. 
Store at -20°C
solubility 
Water: 0.3 mg/ml
form 
A powder
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AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Usage And Synthesis

Description

Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors). It inhibits cAMP accumulation induced by forskolin in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively). Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.

AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALTSupplier

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