ChemicalBook > CAS DataBase List > AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT

AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT

Product Name
AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
CAS No.
54472-66-1
Chemical Name
AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
Synonyms
GHIH;Somatostatin monoacetate;SOMATOSTATIN 14, ACETATE;Cyclic somatostatin Acetate;Somatostatin (sheep), monoacetate (salt);AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT;Somatostatin-14 (human, mouse, rat, porcine, bovine, ovine) (acetate);H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (DISULFIDE BRIDGE: 3-14), ACETATE SALT
CBNumber
CB2166795
Molecular Formula
C78H108N18O21S2
Formula Weight
1697.95
MOL File
Mol file
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AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Property

storage temp. 
Store at -20°C
solubility 
Water: 0.3 mg/ml
form 
A powder
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20809
Product name
Somatostatin-14 (acetate)
Purity
≥98%
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
20809
Product name
Somatostatin-14 (acetate)
Purity
≥98%
Packaging
5mg
Price
$341
Updated
2024/03/01
Cayman Chemical
Product number
20809
Product name
Somatostatin-14 (acetate)
Purity
≥98%
Packaging
10mg
Price
$645
Updated
2024/03/01
Cayman Chemical
Product number
20809
Product name
Somatostatin-14 (acetate)
Purity
≥98%
Packaging
25mg
Price
$1163
Updated
2024/03/01
AK Scientific
Product number
5026EA
Product name
Somatostatinmonoacetate
Packaging
1mg
Price
$179
Updated
2021/12/16
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AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Chemical Properties,Usage,Production

Description

Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors). It inhibits cAMP accumulation induced by forskolin in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively). Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.

References

[1] D J HADJIDAKIS. Differences between somatostatin-28 and somatostatin-14 with respect to their biological effects in healthy humans and acromegalics.[J]. Clinical physiology and biochemistry, 1986, 4 6: 372-383.
[2] S SIEHLER  D H  K Seuwen. Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies.[J]. Naunyn-Schmiedeberg’s archives of pharmacology, 1999, 360 5: 488-499. DOI: 10.1007/s002109900141
[3] S SIEHLER  D H. Characterisation of human recombinant somatostatin receptors. 3. Modulation of adenylate cyclase activity.[J]. Naunyn-Schmiedeberg’s archives of pharmacology, 1999, 360 5: 510-521. DOI: 10.1007/s002109900143
[4] GILLIES G. Somatostatin: the neuroendocrine story.[J]. Trends in pharmacological sciences, 1997, 18 3: 87-95. DOI: 10.1016/s0165-6147(96)01032-2
[5] IAN M P JOSEPH. A model for integrative study of human gastric acid secretion.[J]. Journal of applied physiology, 2003, 94 4: 1602-1618. DOI: 10.1152/japplphysiol.00281.2002

AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
Advantage
62
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Wuhan Dingxintong Pharmaceutical Co. , Ltd.
Tel
15871722230
Fax
2796190295
Email
15871722230@163.com
Country
China
ProdList
4686
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58

54472-66-1, AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALTRelated Search:


  • H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (DISULFIDE BRIDGE: 3-14), ACETATE SALT
  • AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT
  • SOMATOSTATIN 14, ACETATE
  • Somatostatin monoacetate
  • GHIH
  • Somatostatin (sheep), monoacetate (salt)
  • Somatostatin-14 (human, mouse, rat, porcine, bovine, ovine) (acetate)
  • Cyclic somatostatin Acetate
  • 54472-66-1
  • peptide