Vatalanib base Chemical Properties

Melting point:

209-212°

Boiling point:

587.8±50.0 °C(Predicted)

Density 

1.330±0.06 g/cm3(Predicted)

storage temp. 

2-8°C(protect from light)

solubility 

≥16.85 mg/mL in DMSO; ≥3.0125 mg/mL in EtOH with gentle warming and ultrasonic; ≥32.53 mg/mL in H2O with gentle warming and ultrasonic

form 

solid

pka

5.46±0.10(Predicted)

Safety Information

HS Code 

2933399990

Vatalanib base Usage And Synthesis

Uses

Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR, Flt-1 and c-Kit with IC50 of 37 nM, 77 nM and 730 nM, respectively.

Uses

anti-viral

Definition

ChEBI: A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibit r for all isoforms of VEGFR, PDGFR and c-Kit.

Vatalanib base(212141-54-3)Related Product Information

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