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Roxatidine acetate hydrochloride

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Roxatidine acetate hydrochloride Basic information

Product Name:
Roxatidine acetate hydrochloride
Synonyms:
  • ROXATIDINE HCL ACETATE
  • 2-(acetyloxy)-n-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-acetamidmonoh
  • 2-acetoxy-n-(3-(m-(1-piperidinylmethyl)phenoxy)propyl)acetamidehydrochloride
  • 2-hydroxy-n-(3-(m-(piperidinomethyl)phenoxy)propyl)-acetamidacetate(ester
  • 2-hydroxy-n-(3-(m-(piperidinomethyl)phenoxy)propyl)acetamideacetate(ester)
  • aceroxatidinehydrochloride
  • acetamide,2-hydroxy-n-(3-(m-(1-piperidinylmethyl)phenoxy)propyl)-,acetate,
  • tzu0460
CAS:
93793-83-0
MF:
C19H29ClN2O4
MW:
384.89756
EINECS:
685-494-1
Product Categories:
  • Miscellaneous Biochemicals
  • MEFOXIN
  • Amines
  • Aromatics
  • Heterocycles
  • Other APIs
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API
  • 93793-83-0
Mol File:
93793-83-0.mol
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Roxatidine acetate hydrochloride Chemical Properties

Melting point:
145-146°
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO: 78 mg/ml; Ethanol: 12 mg/ml; Water: 77 mg/ml
form 
powder to crystal
color 
White to Almost white
Merck 
14,8274
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Safety Information

RTECS 
AC3855000
HS Code 
2933.39.9200
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Roxatidine acetate hydrochloride Usage And Synthesis

Description

Roxatidine acetate hydrochloride is an H2 antagonist, differing considerably in structure from other marketed agents(cimetidine, ranitidine and famotidine) in this category. It is useful in the treatment of gastric, duodenal and anastomotic ulcers, Zollinger-Ellison syndrome and peptic esophagitis.

Description

Roxatidine acetate is a competitive histamine H2 receptor antagonist that upon oral absorption is rapidly converted to its active metabolite roxatidine. By inhibiting the binding of histamine to H2 receptors, roxatidine reduces both intracellular cAMP concentrations and gastric acid secretion by parietal cells.

Chemical Properties

White Solid

Originator

Teikoku Hormone (Japan)

Uses

antibacterial

Uses

A histamine H2-receptor antagonist. It is used to inhibit gastric acid secretion; an antiulcer agent.

Definition

ChEBI: Roxatidine acetate hydrochloride is a member of piperidines. It contains a Roxane.

brand name

ALTAT

Roxatidine acetate hydrochlorideSupplier

Hubei Chenxin Pharmaceutical Co., Ltd. Gold
Tel
17362916295 17362916295
Email
w17362916295@163.com
Nanjing Shanyao Kangcheng biomedical Co., Ltd. Gold
Tel
15722982350
Email
1170703875@qq.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Email
sales@capotchem.com
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Email
chenyj@titansci.com