ANTI-EPO RECEPTOR Chemical Properties

storage temp. 

−20°C

form 

lyophilized powder

biological source

rabbit

Safety Information

WGK Germany 

WGK 1

Storage Class

12 - Non Combustible Liquids

MSDS

• Language:English Provider:SigmaAldrich

ANTI-EPO RECEPTOR Usage And Synthesis

Uses

Anti-EPOR antibody produced in rabbit has been used in immunoblot analysis and magnetic cell sorting.

Biological Activity

The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and ST at transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and ST at transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Publication Note: This RefSeq record includes a subset of the publications th at are available for this gene. Please see the Entrez Gene record to access additional publications.

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