ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Glycine derivative > Tanogitran
Tanogitran
Tanogitran Basic information
- Product Name:
- Tanogitran
- Synonyms:
-
- Tanogitran
- Glycine, N-[(1R)-1-[2-[[[4-(aMinoiMinoMethyl)phenyl]aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]-1-Methyl-2-oxo-2-(1-pyrrolidinyl)ethyl]-
- MAOALPSHCIBFJZ-RUZDIDTESA-N
- N-[(1R)-1-[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]-1-methyl-2-oxo-2-(1-pyrrolidinyl)ethyl]glycine
- Tanogitran USP/EP/BP
- BIBT 986
- BIBT986
- BIBT-986
- CAS:
- 637328-69-9
- MF:
- C25H31N7O3
- MW:
- 477.56
- Mol File:
- 637328-69-9.mol
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Tanogitran Chemical Properties
- Density
- 1.38
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Tanogitran Usage And Synthesis
Uses
Tanogitran is a dual inhibitor targeting Factor Xa and thrombin (thrombin), with Ki values of 26 and 2.7 nM, respectively. Tanogitran exhibits anticoagulant activity and can be used for research in thrombotic diseases[1][2].
References
[1] Gómez-Outes A, et al. New parenteral anticoagulants in development. Ther Adv Cardiovasc Dis. 2011 Feb;5(1):33-59. DOI:10.1177/1753944710387808
[2] Remko M, et al. Theoretical Study of Molecular Structure and Physicochemical Properties of Novel Factor Xa Inhibitors and Dual Factor Xa and Factor IIa Inhibitors. Molecules. 2016 Feb 4;21(2):185. DOI:10.3390/molecules21020185
TanogitranSupplier
Dideu Industries Group Limited
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Jiangsu Hongmin Pharmaceutical Co., Ltd.
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CONIER CHEM AND PHARMA LIMITED
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Suzhou Meishi Biotechnology Co., Ltd.
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TargetMol Chemicals Inc.
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