4-METHYL-1,3-OXAZOLE-5-CARBOXYLIC ACID Chemical Properties

Melting point:

239 °C

Boiling point:

267.3±20.0 °C(Predicted)

Density 

1.348±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Store in freezer, under -20°C

form 

powder to crystal

pka

2.09±0.31(Predicted)

color 

White to Gray to Brown

InChIKey

ZIXUNDOOBLSXPE-UHFFFAOYSA-N

CAS DataBase Reference

2510-32-9

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

22-36/37/38

Safety Statements 

22-26-36/37/39

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29349990

4-METHYL-1,3-OXAZOLE-5-CARBOXYLIC ACID Usage And Synthesis

Chemical Properties

White to tan solid

Uses

4-Methoxyoxazole-5-carboxylic Acid is used in the synthesis of highly selective α4β2-Nicotinic acetylcholine receptor agonists used in the treatment of cognitive disorders. It is also used in the synthesis of small molecule human FPR1 receptor antagonists.

Uses

Used in a palladium-catalyzed cross-coupling between heteroaryl carboxylic acids and aryl bromides leading to arylated heterocycles.

4-METHYL-1,3-OXAZOLE-5-CARBOXYLIC ACID(2510-32-9)Related Product Information

• Ethyl 4-methyl-1,3-oxazole-5-carboxylate
• 4-METHYLOXAZOLE-5-METHANOL
• 4-METHYL-1,3-OXAZOLE-5-CARBOXYLIC ACID
• 2-METHYL-1,3-OXAZOLE-4-CARBOXYLIC ACID
• 5-(2-METHYL-4-BROMOPHENYL)-OXAZOLE-4-CARBOXYLIC ACID
• 5-METHYL-1,3-OXAZOLE-4-CARBOXYLIC ACID
• OXAZOLE-5-CARBOXYLIC ACID
• 2-AMINO-4-TRIFLUOROMETHYL-OXAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
• METHYL 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-OXAZOLE-5-CARBOXYLATE
• ETHYL 2,4-DIMETHYLOXAZOLE-5-CARBOXYLATE
• ETHYL-2-CHLORO-4-(TRIFLUOROMETHYL)OXAZOLE-5-CARBOXYLATE
• METHYL 4-BENZYL-2-PHENYLOXAZOLE-5-CARBOXYLATE
• 2,4-dimethyl-1,3-oxazole-5-carboxylic acid
• 4-METHYL-2-PHENYL-1,3-OXAZOLE-5-CARBOXYLIC ACID
• METHYL 4-METHYL-2-PHENYL-1,3-OXAZOLE-5-CARBOXYLATE
• 5-methyl-1,2-oxazole-3-carboxylic acid
• 2-METHYL-5-(TRIFLUOROMETHYL)OXAZOLE-4-CARBOXYLIC ACID
• 2-(4-METHOXYPHENYL)-5-METHYL-1,3-OXAZOLE-4-CARBOXYLIC ACID