ARGIPRESSIN ACETATE Chemical Properties

Melting point:

189 °C(dec.)

storage temp. 

−20°C

solubility 

Water: 1 mg/ml

form 

powder to crystal

color 

White to Light yellow

Water Solubility 

Water: 1 mg/ml

Safety Information

Hazard Codes 

Xn

Risk Statements 

20

Safety Statements 

36

WGK Germany 

3

F 

3-10

HS Code 

2937.19.0000

MSDS

• Language:English Provider:SigmaAldrich

ARGIPRESSIN ACETATE Usage And Synthesis

Description

Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V₁, with K_d values of 1.31 and 1.44 nM in A₇r₅ rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively. It also stimulates the intracellular release of calcium in A₇r₅ cells (EC₅₀ = 5 nM). In rat models, argipressin induces hypertension and tachycardia when injected into the lateral septal nuclei at a dose of 100-400 ng and increases heart rate and mean arterial pressure (MAP) when injected into the medial amygdaloid body at a dose of 150-600 ng.

ARGIPRESSIN ACETATE(129979-57-3)Related Product Information

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