Lypressin
Lypressin Basic information
- Product Name:
- Lypressin
- Synonyms:
-
- Lysipressin
- LyspessinAcetate
- (8-lysine)vasopressin
- 8-l-lysine-vasopressi
- CYFQNCPKG-NH2
- LYSINE VASOPRESSIN
- [LYS8]-VASOPRESSIN
- LYPRESSIN
- CAS:
- 50-57-7
- MF:
- C46H65N13O12S2
- MW:
- 1056.22
- EINECS:
- 200-050-5
- Product Categories:
-
- hormones
- Other APIs
- Peptide
- Amino Acid Derivatives
- Mol File:
- 50-57-7.mol
Lypressin Chemical Properties
- Boiling point:
- 1610.4±65.0 °C(Predicted)
- Density
- 1.1080 (rough estimate)
- refractive index
- 1.6700 (estimate)
- storage temp.
- -20°C
- form
- Solid
- pka
- 9.90±0.15(Predicted)
- color
- White to off-white
- Sequence
- H-[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2,(Disulfide bridge: Cys-Cys)
- InChIKey
- NKWAIKZITYLOMT-DHSVNZEYSA-N
- SMILES
- C1(N)CSSCC(C(=O)N2C(C(=O)CC(CCCCN)C(=O)NCC(=O)N)CCC2)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC2C=CC(O)=CC=2)NC1=O)CCC(=O)N
Lypressin Usage And Synthesis
Uses
Hormone (antidiuretic).
Uses
Lypressin is a neurohypophysial hormone that regulates water, glucose, and salts in blood.
Definition
ChEBI: (2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloeicos-4-yl]-oxomethyl]-2-pyrrolidinecarboxamide is a cyclic peptide.
brand name
Pitressin (Parke-Davis).
General Description
Lypressin is synthetic 8-L-lysine vasopressin,a polypeptide similar to ADH. The lysine analog isconsidered more stable, and it is absorbed rapidly from thenasal mucosa. Lypressin (Diapid) is pharmaceutically availableas a topical solution, spray, 50 pressor units(185 g)/mL in 5-mL containers. Usual dosage, topical (intranasal),one or more sprays applied to one or both nostrilsone or more times daily.
Description
Lypressin is a hormone used to prevent or control the frequent urination, increased thirst, and loss of water associated with diabetes insipidus (water diabetes). Its molecular weight is 1056.2 Dalton having an amino acid sequence of Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2. The Molecular Formula is: C46H65N13O12S2.
The CAS Number is: 50-57-7.
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