Lypressin
Lypressin Basic information
- Product Name:
- Lypressin
- Synonyms:
-
- Lysipressin
- LyspessinAcetate
- (8-lysine)vasopressin
- 8-l-lysine-vasopressi
- CYFQNCPKG-NH2
- LYSINE VASOPRESSIN
- [LYS8]-VASOPRESSIN
- LYPRESSIN
- CAS:
- 50-57-7
- MF:
- C46H65N13O12S2
- MW:
- 1056.22
- EINECS:
- 200-050-5
- Product Categories:
-
- hormones
- Other APIs
- Amino Acid Derivatives
- Peptide
- Mol File:
- 50-57-7.mol
Lypressin Chemical Properties
- Boiling point:
- 1610.4±65.0 °C(Predicted)
- Density
- 1.1080 (rough estimate)
- refractive index
- 1.6700 (estimate)
- storage temp.
- -20°C
- form
- Solid
- pka
- 9.90±0.15(Predicted)
- color
- White to off-white
- Sequence
- H-[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2,(Disulfide bridge: Cys-Cys)
- InChIKey
- NKWAIKZITYLOMT-DHSVNZEYSA-N
- SMILES
- C1(N)CSSCC(C(=O)N2C(C(=O)CC(CCCCN)C(=O)NCC(=O)N)CCC2)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC2C=CC(O)=CC=2)NC1=O)CCC(=O)N
Lypressin Usage And Synthesis
Uses
Hormone (antidiuretic).
Uses
Lypressin is a neurohypophysial hormone that regulates water, glucose, and salts in blood.
Definition
ChEBI: (2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloeicos-4-yl]-oxomethyl]-2-pyrrolidinecarboxamide is a cyclic peptide.
brand name
Pitressin (Parke-Davis).
General Description
Lypressin is synthetic 8-L-lysine vasopressin,a polypeptide similar to ADH. The lysine analog isconsidered more stable, and it is absorbed rapidly from thenasal mucosa. Lypressin (Diapid) is pharmaceutically availableas a topical solution, spray, 50 pressor units(185 g)/mL in 5-mL containers. Usual dosage, topical (intranasal),one or more sprays applied to one or both nostrilsone or more times daily.
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