Basic information Safety Supplier Related

HYDROETHIDINE

Basic information Safety Supplier Related

HYDROETHIDINE Basic information

Product Name:
HYDROETHIDINE
Synonyms:
  • DHE
  • DIHYDROETHIDIUM
  • HYDROETHIDINE
  • HYDROETHIDINE(TM)
  • 5,6-dihydro-3,8-diamino-5-ethyl-6-phenyl-phenanthridin
  • 2,7-DIAMINO-10-ETHYL-9-PHENYL-9,10-DIHYDROPHENANTHRIDINE
  • 3,8-DIAMINO-5,6-DIHYDRO-5-ETHYL-6-PHENYLPHENANTHRIDINE
  • 5,6-dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine
CAS:
38483-26-0
MF:
C21H21N3
MW:
315.41
EINECS:
604-604-1
Product Categories:
  • A1-ALAntibodies for Kinase/Phosphatase Biology
  • Activins and InhibinsCell Biology
  • ActivinsCytokines, Growth Factors and Hormones
  • Alphabetical Index
  • Antibodies
  • Antibodies to Activins and InhibinsNeural Stem Cell Biology
  • pharmacetical
  • Antibodies to Cytokines and Growth Factors
  • Cytokines and Growth Factors
  • Neural Markers
  • Neural Stem Cell Tracking
  • Tyrosine Kinase-Like Antibodies
Mol File:
38483-26-0.mol
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HYDROETHIDINE Chemical Properties

Boiling point:
444.96°C (rough estimate)
Density 
1.1227 (rough estimate)
refractive index 
1.6380 (estimate)
storage temp. 
−20°C
solubility 
acetonitrile: soluble
CAS DataBase Reference
38483-26-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
36/37/38-22
Safety Statements 
37/39-26
WGK Germany 
3
8-10

MSDS

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HYDROETHIDINE Usage And Synthesis

Uses

Dihydroethidium, also known as hydroethidine, is a dye that can permeate viable cells and accumulate in the nucleus after it is dehydrogenated to ethidium bromide and is used to measure oxygen reduction in phagocytes during respiratory burst. In the presence of an oxidant it will fluoresce and has been used as a dye in flow cytometry. Studies have used Dihydroethidium to study alveolar macrophages, blood leukocytes, and epithelial cells, among others, and has be used to measure intracellular H2O2 and O2-, and reactive oxygen. Dyes and metabolites.

General Description

A cell-permeable, chemically reduced ethidium derivative that can be used as a fluorogenic probe for the detection of reactive oxygen species (ROS). It undergoes significant oxidation in resting leukocytes, possibly through the uncoupling of mitochondrial oxidative phosphorylation. Cytosolic dihydroethidium displays blue fluorescence, however, following oxidation to ethidium and subsequent intercalation to DNA, a bright red fluorescence is achieved. Often used to determine the level of superoxide anion in cells by flow cytometry.

Biochem/physiol Actions

Cell permeable: yes

HYDROETHIDINESupplier

Beijing Ouhe Technology Co., Ltd
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010-82967028 13552068683
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2355560935@qq.com
Shanghai Macklin Biochemical Co.,Ltd.
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15221275939
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shenlinxing@macklin.cn
Chuzhou KeMail Chemical Technology Co., Ltd
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0550-5196001 15000891977
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wj520wjxby@126.com
Aishilun biotechnology (Shanghai) co., LTD
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021-50676523 18019098996
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info@acelybio.com
Career Henan Chemica Co
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+86-0371-86658258
Email
laboratory@coreychem.com