HYDROETHIDINE
HYDROETHIDINE Basic information
- Product Name:
- HYDROETHIDINE
- Synonyms:
-
- DHE
- DIHYDROETHIDIUM
- HYDROETHIDINE
- HYDROETHIDINE(TM)
- 5,6-dihydro-3,8-diamino-5-ethyl-6-phenyl-phenanthridin
- 2,7-DIAMINO-10-ETHYL-9-PHENYL-9,10-DIHYDROPHENANTHRIDINE
- 3,8-DIAMINO-5,6-DIHYDRO-5-ETHYL-6-PHENYLPHENANTHRIDINE
- 5,6-dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine
- CAS:
- 38483-26-0
- MF:
- C21H21N3
- MW:
- 315.41
- EINECS:
- 604-604-1
- Product Categories:
-
- A1-ALAntibodies for Kinase/Phosphatase Biology
- Activins and InhibinsCell Biology
- ActivinsCytokines, Growth Factors and Hormones
- Alphabetical Index
- Antibodies
- Antibodies to Activins and InhibinsNeural Stem Cell Biology
- pharmacetical
- Antibodies to Cytokines and Growth Factors
- Cytokines and Growth Factors
- Neural Markers
- Neural Stem Cell Tracking
- Tyrosine Kinase-Like Antibodies
- Mol File:
- 38483-26-0.mol
HYDROETHIDINE Chemical Properties
- Boiling point:
- 444.96°C (rough estimate)
- Density
- 1.1227 (rough estimate)
- refractive index
- 1.6380 (estimate)
- storage temp.
- −20°C
- solubility
- acetonitrile: soluble
- CAS DataBase Reference
- 38483-26-0(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 37/39-26
- WGK Germany
- 3
- F
- 8-10
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
HYDROETHIDINE Usage And Synthesis
Uses
Dihydroethidium, also known as hydroethidine, is a dye that can permeate viable cells and accumulate in the nucleus after it is dehydrogenated to ethidium bromide and is used to measure oxygen reduction in phagocytes during respiratory burst. In the presence of an oxidant it will fluoresce and has been used as a dye in flow cytometry. Studies have used Dihydroethidium to study alveolar macrophages, blood leukocytes, and epithelial cells, among others, and has be used to measure intracellular H2O2 and O2-, and reactive oxygen. Dyes and metabolites.
General Description
A cell-permeable, chemically reduced ethidium derivative that can be used as a fluorogenic probe for the detection of reactive oxygen species (ROS). It undergoes significant oxidation in resting leukocytes, possibly through the uncoupling of mitochondrial oxidative phosphorylation. Cytosolic dihydroethidium displays blue fluorescence, however, following oxidation to ethidium and subsequent intercalation to DNA, a bright red fluorescence is achieved. Often used to determine the level of superoxide anion in cells by flow cytometry.
Biochem/physiol Actions
Cell permeable: yes
HYDROETHIDINESupplier
- Tel
- 010-82967028 13552068683
- 2355560935@qq.com
- Tel
- 0550-5196001 15000891977
- wj520wjxby@126.com
- Tel
- 021-50676523 18019098996
- info@acelybio.com
- Tel
- +1-5166625404
- Info@alfa-chemistry.com
- Tel
- +86-0371-86658258 15093356674;
- laboratory@coreychem.com
HYDROETHIDINE(38483-26-0)Related Product Information
- DIHYDROETHIDIUM (HYDROETHIDINE),DIHYDROETHIDIUM (HYDROETHIDINE)
- DIHYDROETHIDIUM, FOR FLUORESCENCE*,(DIHYDROETHIDIUM BROMIDE),HYDROETHIDINE™,hydroethidine(dihydroethidiumbromide)
- HYDROETHIDINE (DS 1354)
- 2'-METHYL-BIPHENYL-2-YLAMINE
- 3-(1-AMINO-ETHYL)-PHENYLAMINE
- 5-ETHYL-5,6-DIHYDRO-3,8-DINITRO-6-PHENYL-6-PHENANTHRIDINOL
- (2-methylphenyl)(phenyl)methylamine
- 3-AMINO-N,N-DIMETHYLBENZYLAMINE
- HYDROETHIDINE
- N1,N1,6-trimethylbenzene-1,3-diamine