DIHYDROETHIDIUM
DIHYDROETHIDIUM Basic information
- Product Name:
- DIHYDROETHIDIUM
- Synonyms:
-
- HYDROETHIDINE; PD-MY 003
- 5-ethyl-6-phenyl-5,6-dihydrophenanthridine-3,8-diaMine
- Hydroethidine,98%
- PD-MY 003
- 3,8-Phenanthridinediamine,5-ethyl-5,6-dihydro-6-phenyl-
- 2,7-Diamino-10-ethyl-9-phenyl-9,10-dihydrophenanthridine 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine Hydroethidine
- DIHYDROETHIDIUM, FOR FLUORESCENCE*
- (DIHYDROETHIDIUM BROMIDE)
- CAS:
- 104821-25-2
- MF:
- C21H21N3
- MW:
- 315.41
- Product Categories:
-
- Inhibitors
- Phenanthridine
- Mol File:
- 104821-25-2.mol
DIHYDROETHIDIUM Chemical Properties
- Boiling point:
- 580.4±50.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- acetonitrile: soluble
- pka
- 5.30±0.40(Predicted)
- form
- powder
- color
- Pink to dark brown
- λmax
- 355 nm
- BRN
- 5107482
- Biological Applications
- Apoptosis assay; generating and detecting reactive oxygen species (ROS); detecting nucleic acids,cells; measuring respiratory burst; superoxide indicator; viability assay
Safety Information
- WGK Germany
- 3
- F
- 8-10
- HS Code
- 29339900
DIHYDROETHIDIUM Usage And Synthesis
Chemical Properties
DIHYDROETHIDIUM is pink to purple fine crystalline powder
Uses
DIHYDROETHIDIUM is redox indicator. Blue fluorescence until oxidized to ethidium. Can be used for detecting superoxide radical in cells, tissues and organisms.
Uses
Dihydroethidium, also known as hydroethidine, is a dye that can permeate viable cells and accumulate in the nucleus after it is dehydrogenated to ethidium bromide and is used to measure oxygen reduction in phagocytes during respiratory burst. In the presence of an oxidant it will fluoresce and has been used as a dye in flow cytometry. Studies have used Dihydroethidium to study alveolar macrophages, blood leukocytes, and epithelial cells, among others, and has be used to measure intracellular H2O2 and O2-, and reactive oxygen. Dyes and metabolites.
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