Basic information Safety Supplier Related

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID

Basic information Safety Supplier Related

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID Basic information

Product Name:
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID
Synonyms:
  • DELTA12-PROSTAGLANDIN D2
  • 9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID
  • (5z,9-alpha,12e,15s)-9,15-dihydroxy-11-oxoprosta-5,12-dien-1-oicacid
  • 9,15-dihydroxy-11-oxo-,(5z,9-alpha,12e,15s)-prosta-12-dien-1-oicacid
  • delta(sup12)-pgd2
  • delta(sup12)-prostaglandind2
  • (5Z,12E,15S)-9α,15-Dihydroxy-11-oxoprosta-5,12-dien-1-oic acid
  • Δ12-PGD2
CAS:
64072-89-5
MF:
C20H32O5
MW:
352.47
Mol File:
64072-89-5.mol
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9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID Chemical Properties

solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 2 mg/ml
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9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID Usage And Synthesis

Description

Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, hematopoietic-type PGD synthase. PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. Δ12-PGD2 is one of the initial chemical decomposition products of PGD2. Δ12-PGD2 is an intermediate in the pathway leading to Δ12-PGJ2, which is a cyclopentenone prostaglandin with antimitotic and carcinogenic activities. The metabolism of Δ12-PGD2 involves addition of thiol nucleophiles, as is the case with the majority of cyclopentenone prostaglandins.

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACIDSupplier

Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
Tel
0571-85361029
Email
synstar518@163.com
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Email
sales@chemegen.com
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
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9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID(64072-89-5)Related Product Information