MEGA-10 Chemical Properties

Melting point:

91-93 °C

Boiling point:

595.8±50.0 °C(Predicted)

Density 

1.155±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

H₂O: 10 mg/mL at 20 °C, clear, colorless

pka

13.44±0.20(Predicted)

form 

Solid

color 

White to Off-White

Water Solubility 

Soluble in methanol at 50mg/ml. Also soluble in water at 10mg/ml 20 °C

BRN 

6974359

EPA Substance Registry System

N-Oxodecyl meglumine (85261-20-7)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

22-24/25-37/39-36-26

WGK Germany 

3

F 

3-9

MSDS

• Language:English Provider:SigmaAldrich

MEGA-10 Usage And Synthesis

Uses

Non-ionic detergent for solubilizing membrane proteins

Purification Methods

Possible impurities are decanoic acid and N-methylglycamine. The former is removed by grinding the solid with Et2O and then with pet ether and drying over P2O5. It is twice recrystallised from MeOH/Et2O by dissolving in the minimum volume of MeOH, adding Et2O and drying in a vacuum. To remove the glycamine, the solid (800mg) is dissolved in hot H2O (10mL) and set aside. Mega-10 crystallises as colourless needles. These are filtered off and dried in a vacuum to constant weight. It is a good non-ionic non-hygroscopic detergent with a critical micelle concentration (CMC) of 7.4mM (0.26%) in 0.1M Tris-HCl pH 7.4 at 25o. [Hildreth Biochem J 207 363 1982.]

MEGA-10(85261-20-7)Related Product Information

• MEGA-9
• MEGA-8
• Meglumine
• N-DECYL-BETA-D-GLUCOPYRANOSIDE
• DECANAMIDE
• N,N-Dimethylcapramide
• 6-DIMETHYLAMINO-1-HEXANOL
• N,N-DIMETHYLHEXANAMIDE
• N-(N-OCTYL)-N-PENTYLAMINE
• 4-(N-BUTYLAMINO)-1-BUTANOL
• MEGA-10
• N,N-Dimethyloctanamide
• N-METHYLDIHEXYLAMINE
• N,N-DIMETHYLPIMELAMIDE
• N,N-DIMETHYLVALERAMIDE
• MEGA-10--N/H
• MEGA-12
• N-Caproylethanolamine