Ethyl 6-chloronicotinate
Ethyl 6-chloronicotinate Basic information
- Product Name:
- Ethyl 6-chloronicotinate
- Synonyms:
-
- 3-Pyridinecarboxylic acid, 6-chloro-, ethyl ester
- ETHYL 6-CHLORONICOTINATE[FOR TAZAROTENE]
- Ethyl 6-chloropyridine-3-carboxylate
- ETHYL 2-CHLOROPYRIDINE-5-CARBOXYLATE
- Ethyl 6-chloronicoti
- 2-Chloro-5-pyridinecarboxylicacid ethylester
- Ethyl6-chloronicotinate,97%
- Ethyl 2-chloropyridine-3-carboxylate, 6-Chloronicotinic acid ethyl ester
- CAS:
- 49608-01-7
- MF:
- C8H8ClNO2
- MW:
- 185.61
- EINECS:
- 610-463-6
- Product Categories:
-
- Building Blocks
- C7 to C18
- C8 to C9
- Chemical Synthesis
- Halogenated Heterocycles
- Heterocyclic Building Blocks
- Esters
- Pyridines
- Heterocycle-Pyridine series
- carboxylic ester| alkyl chloride
- Mol File:
- 49608-01-7.mol
Ethyl 6-chloronicotinate Chemical Properties
- Melting point:
- 26-30 °C(lit.)
- Boiling point:
- 98 °C
- Density
- 1.245±0.06 g/cm3(Predicted)
- refractive index
- 1.522
- Flash point:
- >230 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- -1.95±0.10(Predicted)
- color
- Colourless to Off-White Oil
- BRN
- 4742175
- InChIKey
- ILDJJTQWIZLGPO-UHFFFAOYSA-N
- CAS DataBase Reference
- 49608-01-7(CAS DataBase Reference)
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
Ethyl 6-chloronicotinate Usage And Synthesis
Chemical Properties
White to light yellow solid or colorless to yellow liquid
Uses
Ethyl 6-chloropyridine-3-carboxylate (Ethyl 6-chloronicotinate) may be used in the preparation of ethyl 5-{[5-(1H-benzimidazol-2-yl)pyridin-2-yl]ethynyl}pyridine-2-carboxylate by reacting with 2-[6-(ethynyl)pyridin-3-yl]-1H-benzimidazole under microwave irradiation.
Uses
Ethyl 6-chloronicotinate is a nicotinic acid derivative used in the preparation of potent H3 receptor antagonists.
General Description
Ethyl 6-chloropyridine-3-carboxylate (Ethyl-6-chloronicotinate, E-6-ClN) undergoes direct amidation on reacting with benzylamine in the presence lanthanum trifluoromethanesulfonate La(OTf)3. The structural and physicochemical properties of E-6-ClN have been investigated based on its spectroscopic data, time-dependent density functional theory and density of state diagrams.
Ethyl 6-chloronicotinate Preparation Products And Raw materials
Preparation Products
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Ethyl 6-chloronicotinate(49608-01-7)Related Product Information
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