DMEOB
DMEOB Basic information
- Product Name:
- DMEOB
- Synonyms:
-
- DMEOB
- [(3-METHOXYPHENYL)METHYLENE]HYDRAZONE-3-METHOXYBENZALDEHYDE
- 3-METHOXYBENZALDEHYDE [(3-METHOXYPHENYL)METHYLENE]HYDRAZONE
- bis(3-methoxybenzylidene)hydrazine
- Benzaldehyde, 3-methoxy-, 2-[(3-methoxyphenyl)methylene]hydrazone
- 1,2-Bis(3-methoxybenzylidene)hydrazine
- CAS:
- 40252-74-2
- MF:
- C16H16N2O2
- MW:
- 268.31
- Product Categories:
-
- Glutamate receptor
- Mol File:
- 40252-74-2.mol
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DMEOB Chemical Properties
- Melting point:
- 77-78 °C(Solv: ethanol (64-17-5))
- Boiling point:
- 405.1±45.0 °C(Predicted)
- Density
- 1.05±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: insoluble
- form
- solid
- pka
- 6.46±0.50(Predicted)
- color
- yellow
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Safety Information
- Hazard Codes
- Xi,N
- Risk Statements
- 41-50/53
- Safety Statements
- 26-36/37/39-60-61
- RIDADR
- UN 3077 9/PG 3
- WGK Germany
- 3
MSDS
- Language:English Provider:SigmaAldrich
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DMEOB Usage And Synthesis
Uses
DMEOB is a negative allosteric modulator at mGluR-5 (1). These mGlu receptors maintain a modulatory role and act as drug targets for various neurological disorders including depression, schizophrenia and Parkinson’s.
Biological Activity
Negative allosteric modulator of the metabotropic glutamate receptor mGlu 5 ; displays reversible non-competitive inhibition of mGlu 5 -mediated responses (IC 50 = 3 μ M).
Biochem/physiol Actions
Negative allosteric modulator at the metabotropic glutamate receptor mGluR5.
DMEOBSupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
MQ (shanghai) Pharmaceuticals Co., Ltd.
- Tel
- 13761635123
- 1014988033@qq.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com