3-Methoxybenzaldehyde Chemical Properties

Melting point:

187 °C

Boiling point:

143 °C50 mm Hg(lit.)

Density 

1.117 g/mL at 20 °C(lit.)

vapor pressure 

1.3 hPa (73 °C)

refractive index 

n20/D 1.553(lit.)

Flash point:

>230 °F

storage temp. 

Store below +30°C.

solubility 

Chloroform, Methanol (Slightly)

form 

Liquid

color 

Clear pale yellow to yellow

Specific Gravity

1.118

Odor

at 100.00?%. anisic

Water Solubility 

insoluble

Sensitive 

Air Sensitive

BRN 

606013

LogP

1.710

CAS DataBase Reference

591-31-1(CAS DataBase Reference)

NIST Chemistry Reference

Benzaldehyde, 3-methoxy-(591-31-1)

EPA Substance Registry System

Benzaldehyde, 3-methoxy- (591-31-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-36/38

Safety Statements 

26-36-37/39

WGK Germany 

3

RTECS 

BZ2605000

F 

9-23

Autoignition Temperature

225 °C

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29124900

Toxicity

sce-hmn:lyms 1 mmol/L MUREAV 206,17,88

MSDS

• Language:English Provider:m-Anisaldehyde
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Methoxybenzaldehyde Usage And Synthesis

Chemical Properties

clear pale yellow to yellow liquid

Uses

3-Methoxybenzaldehyde is used to prepare 3-(3-methoxy-phenyl)-1-phenyl-propenone by reaction with benzldehyde. It is used as an eluent for mono-13C isotopomers of vanillin in normal phase silica gel chromatography. It acts as an inhibitor of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism.

Definition

ChEBI: 3-methoxybenzaldehyde is a member of the class of benzaldehydes in which the hydrogen at position 3 of benzaldehyde has been replaced by a methoxy group. It has a role as a Brassica napus metabolite. It is a member of benzaldehydes and a monomethoxybenzene.

Synthesis Reference(s)

Synthetic Communications, 24, p. 2011, 1994 DOI: 10.1080/00397919408010209

General Description

m-Anisaldehyde has significant antifungal activity against Candida sp., including the azole-resistant strains.

Safety Profile

Mutation data reported. Whenheated to decomposition it emits acrid smoke andirritating vapors.

Purification Methods

Wash it with saturated aqueous NaHCO3, then H2O, dry it with anhydrous MgSO4 and distil it under reduced pressure under N2. Store it under N2 in sealed glass ampoules. [Beilstein 8 IV 241.]

3-Methoxybenzaldehyde(591-31-1)Related Product Information

• p-Anisaldehyde
• Anisole
• p-Anisidine
• Benzaldehyde
• (Trifluoromethoxy)benzene
• Veratraldehyde
• 3,5-Dimethoxybenzaldehyde
• 4-Hydroxybenzaldehyde
• 2,4-Dimethoxybenzaldehyde
• 2,3-Dimethoxybenzaldehyde
• 2,6-Dimethoxybenzaldehyde
• 3-(METHOXYMETHOXY)BENZALDEHYDE
• 2,5-Dimethoxybenzoic acid
• 2,3-Dimethoxybenzoic acid
• 3-Methoxysalicylic acid
• 5-Methoxy-3,4-dihydro-2H-naphthalen-1-one
• 2-BROMO-2',5'-DIMETHOXYACETOPHENONE
• o-Anisaldehyde