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3-Methoxysalicylic acid

Basic information Safety Supplier Related

3-Methoxysalicylic acid Basic information

Product Name:
3-Methoxysalicylic acid
Synonyms:
  • 2-hydroxy-3-methoxy-benzoicaci
  • 2-hydroxy-m-anisicaci
  • 3-Methoxysalicylic acid,97%
  • 3-Methoxysalicylic a
  • 3-Methoxysalicylic acid, 97% 25GR
  • Guaiacol-3-carboxylic Acid 2-Hydroxy-3-methoxybenzoic Acid o-Vanillic Acid
  • Benzoic acid,2-hydroxy-3-Methoxy-
  • 2-Hydroxy-3-methoxybenzoic acid, >=99%
CAS:
877-22-5
MF:
C8H8O4
MW:
168.15
EINECS:
212-888-9
Product Categories:
  • Organic acids
  • Miscellaneous
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • BUILDING BLOCKS
Mol File:
877-22-5.mol
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3-Methoxysalicylic acid Chemical Properties

Melting point:
147-150 °C(lit.)
Boiling point:
217.07°C (rough estimate)
Density 
1.1816 (rough estimate)
refractive index 
1.4611 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
2.85±0.10(Predicted)
form 
Solid
color 
Off-White to Beige
BRN 
2209642
LogP
1.940
CAS DataBase Reference
877-22-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-37/39-36
WGK Germany 
3
RTECS 
BZ4840000
HS Code 
29189900

MSDS

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3-Methoxysalicylic acid Usage And Synthesis

Chemical Properties

beige powder

Uses

o-Vanillic Acid, is a derivative of Vanillic Acid (V097350), used as a flavoring agent. o-Vanillic Acid, is also a building block used for the synthesis of more complex pharmaceutical compounds such as Warfarin (W498500), and Phenprocoumon (P318820).

Uses

2-Hydroxy-3-methoxybenzoic acid was used as internal standard during the simultaneous quantification of acetylsalicylic acid and its metabolite salicylic acid in human plasma by high-performance liquid chromatography. It was used in large-scale synthesis of 7-methoxy-3(2H)-benzofuranone.

Definition

ChEBI: 3-methoxysalicylic acid is benzoic acid substituted with a hydroxy group at position C-2 and a methoxy group at position C-3. It has a role as a metabolite.

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