3-Methoxybenzoic acid Chemical Properties

Melting point:

105-107 °C (lit.)

Boiling point:

170-172 °C/10 mmHg (lit.)

Density 

1.2143 (rough estimate)

refractive index 

1.4945 (estimate)

FEMA 

3944 | 3-METHOXYBENZOIC ACID

Flash point:

170-172°C/10mm

storage temp. 

Sealed in dry,Room Temperature

solubility 

95% ethanol: soluble50mg/mL, clear, colorless to faintly yellow

form 

Powder

pka

4.10(at 25℃)

color 

Off-white to slightly yellow-beige

Water Solubility 

Soluble in 95% ethanol (50 mg/ml), water (2 mg/ml at 25°C) and methanol.

JECFA Number

882

BRN 

508838

InChIKey

XHQZJYCNDZAGLW-UHFFFAOYSA-N

LogP

2.02

CAS DataBase Reference

586-38-9(CAS DataBase Reference)

NIST Chemistry Reference

Benzoic acid, 3-methoxy-(586-38-9)

EPA Substance Registry System

Benzoic acid, 3-methoxy- (586-38-9)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-22-20/21/22

Safety Statements 

26-36-24/25

WGK Germany 

3

RTECS 

BZ4375000

F 

3

TSCA 

Yes

HS Code 

29189090

Toxicity

LDLo ipr-mus: 250 mg/kg CBCCT* 6,144,54

MSDS

• Language:English Provider:3-Methoxybenzoic acid
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-Methoxybenzoic acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Chemical Properties

3-Methoxybenzoic acid is practically odorless.

Uses

3-Methoxybenzoic acid is used in the synthesis and characterization of 3-methoxybenzoates of europium (III) and gadolinium (III)1. It was used in conversion of aromatic carboxylic acids into methyl esters and reduction to the corresponding primary alcohols using a sodium borohydride-THF-methanol system

Definition

ChEBI: 3-methoxybenzoic acid is a methoxybenzoic acid that is benzoic acid substituted by a methoxy group at position 3. It has a role as a flavouring agent and a human urinary metabolite. It is functionally related to a 3-hydroxybenzoic acid. It is a conjugate acid of a 3-methoxybenzoate.

General Description

3-Methoxybenzoic acid is an important intermediate in the synthesis of natural products.

Safety Profile

Poison by intraperitoneal route.When heated to decomposition it emits acrid smoke andirritating fumes.

Purification Methods

Crystallise m-anisic acid from H2O (m 109o, 110.5o) or EtOH/water. The S-benzylisothiuronium salt has m 176o (from EtOH). [Beilstein 10 II 80, 10 III 244, 10 IV 316.]

3-Methoxybenzoic acid(586-38-9)Related Product Information

• Anisole
• 3,4-Dimethoxybenzoic acid
• Ethyl 2-(Chlorosulfonyl)acetate
• 4-Methoxybenzylchloride
• 2,6-Dimethoxybenzoic acid
• Folic acid
• Citric acid
• 3-Methoxybenzaldehyde
• (Trifluoromethoxy)benzene
• 3-Chloroperoxybenzoic acid
• 3-(Trifluoromethyl)benzoic acid
• m-Toluic acid
• (3-Methoxyphenyl)acetonitrile
• 3-Hydroxybenzoic acid
• 3-(METHOXYMETHOXY)BENZALDEHYDE
• Hyaluronic acid
• 3,5-Dimethoxybenzoic acid
• p-Anisaldehyde