Alcohols spices Phenols, ethers and epoxides Halogen, sulfur, nitrogen compounds Oxygen-containing heterocyclic compounds Aldehydes spices Macrocyclic musks Carboxylic acids and esters carbonyl spices Hydrocarbon spices Ketones spices Thiols spices Thioethers spices Pyrazine spices Aromatic acid, ester and derivatives
ChemicalBook >   Product Catalog >  Flavors and fragrances >  Synthetic fragrances

Synthetic fragrances

Alcohols spices Phenols, ethers and epoxides Halogen, sulfur, nitrogen compounds Oxygen-containing heterocyclic compounds Aldehydes spices Macrocyclic musks Carboxylic acids and esters carbonyl spices Hydrocarbon spices Ketones spices Thiols spices Thioethers spices Pyrazine spices Aromatic acid, ester and derivatives
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Synthetic fragrances is also known as artificially synthetic fragrance. It is a mimic of the natural flavors manufactured using science and technology by human beings. It refers to a “single-one” spice manufactured or prepared through chemical or biological pathways using different raw materials. Currently, there are already 5000 kinds of Synthetic fragrances in the world with 400 kinds of them belonging to commonly used products. Synthetic fragrances industry has become an important part of fine organic chemical industry.

Synthetic fragrances, according to their chemical structure or functional groups, can be divided into hydrocarbons, alcohols, acids, esters, lactones, aldehydes, ketones, phenols, ethers, acetals, ketals, shiff base, nitrile, macrocyclic, polycyclic, heterocyclic (pyrazine, pyridine, furan furosemide thiazole, etc.), sulfides, halides and so on.

The GB2760 in China allows the application of more than 257 kinds of Synthetic fragrances in the food flavors directories. The commonly used Synthetic fragrances in the beverage can be divided into esters and non-esters, two kinds.
(1) Synthetic esters spices: the esters of organic acids and alcohols, due to undergoing alkali saponification, generally have poor alkali resistance except the third class terpene alcohol esters (terpinyl acetate, linalyl acetate). The esters spices are generally prepared through the esterification of organic acids and alcohols. Among the esters spices listed in Table 1-4-21, acetate esters occupy the majority, up to 12 species. From the component of the alcohol, the number of alcohol ester is 11; the number of iso-amyl alcohol esters is 7; the number of methyl ester is 5. These kinds of esters are all difficultly soluble or almost insoluble in water, but being easily soluble in alcohol and ether. Owing to the highly volatility, it must be sealed and stored in a cool dark place. These esters spices are rarely used alone and are generally blended with a variety of other spices for application.
(2) Non-ester spices are mainly spices including alcohols, aldehydes, volatile acids, and ketones that exclude ester spices, wherein the aldehyde, the phenol and structure having unstable double bond occupies the majority of them. They can be easily oxidized in the air and should be given full attention.
In particular, the aromatic aldehydes that can have cannizarro reaction such as anisaldehyde, vanillin, ethyl vanillin, benzaldehyde, pepper aldehyde and aldehyde having double bond nearly to the aldehyde group (α- amyl cinnamaldehyde, cinnamic aldehyde and citral) are non-unstable esters spices. They are rarely used alone except vanillin and menthol with being blended with other spices for application in most cases.

Artificial spices are flavor components that have not been identified in the natural product (no matter whether or not processed) for human consumption. Such spices have fewer varieties with all of them manufactured by chemical methods, and their chemical structures have not yet been found in nature.
Based on this, the safety of these spices has drawn a lot of attention. In China, those spices included in the GB/T14156-93 "edible spices and coding" all have undergone certain toxicological evaluation, and are considered harmless to humans (in certain doses). Among them, except individual spices undergoing adequate toxicological evaluation, they are all currently classified as temporary license. It should be noted that, with the continuous development of science and technology and human awareness, some varieties originally belonging to artificial spice varieties have also found in some natural foods, thus being classified as nature-identical flavors. For example, the artificial spice, allyl caproate, temporarily used in China is now re-classified as nature-identical spice internationally.

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Structure:
Chemical Name:
2,6-Dimethoxyphenol
CAS:
91-10-1
MF:
C8H10O3
Structure:
Chemical Name:
4-Propylphenol
CAS:
645-56-7
MF:
C9H12O
Structure:
Chemical Name:
2-Pyrazinylethanethiol
CAS:
35250-53-4
MF:
C6H8N2S
Structure:
Chemical Name:
Citronellol
CAS:
106-22-9
MF:
C10H20O
Structure:
Chemical Name:
2-Thienyl disulfide
CAS:
6911-51-9
MF:
C8H6S4
Structure:
Chemical Name:
Hydroxyacetone
CAS:
116-09-6
MF:
C3H6O2
Structure:
Chemical Name:
2,3,6-Trimethylphenol
CAS:
2416-94-6
MF:
C9H12O
Structure:
Chemical Name:
3-Heptanone
CAS:
106-35-4
MF:
C7H14O
Structure:
Chemical Name:
2-Pentanol
CAS:
6032-29-7
MF:
C5H12O
Structure:
Chemical Name:
trans-2-Hexenoic acid
CAS:
13419-69-7
MF:
C6H10O2
Structure:
Chemical Name:
Cinnamaldehyde
CAS:
104-55-2
MF:
C9H8O
Structure:
Chemical Name:
5-METHYLQUINOXALINE
CAS:
13708-12-8
MF:
C9H8N2
Structure:
Chemical Name:
alpha-Ionone
CAS:
127-41-3
MF:
C13H20O
Structure:
Chemical Name:
Benzaldehyde propylene glycol acetal
CAS:
2568-25-4
MF:
C10H12O2
Structure:
Chemical Name:
PROPYL BENZOATE
CAS:
2315-68-6
MF:
C10H12O2
Structure:
Chemical Name:
Methyl valeraldehyde
CAS:
123-15-9
MF:
C6H12O
Structure:
Chemical Name:
Dimethyl adipate
CAS:
627-93-0
MF:
C8H14O4
Structure:
Chemical Name:
4-Methylthiazole
CAS:
693-95-8
MF:
C4H5NS
Structure:
Chemical Name:
4-Methylvaleric acid
CAS:
646-07-1
MF:
C6H12O2
Structure:
Chemical Name:
α-Methylcinnamaldehyde
CAS:
101-39-3
MF:
C10H10O
Structure:
Chemical Name:
Benzothiazole
CAS:
95-16-9
MF:
C7H5NS
Structure:
Chemical Name:
L(-)-Carvone
CAS:
6485-40-1
MF:
C10H14O
Structure:
Chemical Name:
2,5-Dimethyl-1H-pyrrole
CAS:
625-84-3
MF:
C6H9N
Structure:
Chemical Name:
Ethyl butyrylacetate
CAS:
3249-68-1
MF:
C8H14O3
Structure:
Chemical Name:
2-METHOXYTHIAZOLE
CAS:
14542-13-3
MF:
C4H5NOS
Structure:
Chemical Name:
4-Ethylphenol
CAS:
123-07-9
MF:
C8H10O
Structure:
Chemical Name:
trans,trans-2,4-Decadien-1-al
CAS:
25152-84-5
MF:
C10H16O
Structure:
Chemical Name:
alpha-Hexylcinnamaldehyde
CAS:
101-86-0
MF:
C15H20O
Structure:
Chemical Name:
Sclareol
CAS:
515-03-7
MF:
C20H36O2
Structure:
Chemical Name:
DL-3-Methylvaleric acid
CAS:
105-43-1
MF:
C6H12O2
Structure:
Chemical Name:
2-Nonanone
CAS:
821-55-6
MF:
C9H18O
Structure:
Chemical Name:
2-Methylthiophene
CAS:
554-14-3
MF:
C5H6S
Structure:
Chemical Name:
4-Hexanolide
CAS:
695-06-7
MF:
C6H10O2
Structure:
Chemical Name:
2-Acetylfuran
CAS:
1192-62-7
MF:
C6H6O2
Structure:
Chemical Name:
Ethyl benzoylacetate
CAS:
94-02-0
MF:
C11H12O3
Structure:
Chemical Name:
4,5-Dimethyl-2-isobutyl-3-thiazoline
CAS:
65894-83-9
MF:
C9H17NS
Structure:
Chemical Name:
3-Methylthiophene
CAS:
616-44-4
MF:
C5H6S
Structure:
Chemical Name:
3-Methoxybenzoic acid
CAS:
586-38-9
MF:
C8H8O3
Structure:
Chemical Name:
alpha-Angelica lactone
CAS:
591-12-8
MF:
C5H6O2
Structure:
Chemical Name:
2,5-Dimethylfuran
CAS:
625-86-5
MF:
C6H8O
Structure:
Chemical Name:
2',4'-Dimethylacetophenone
CAS:
89-74-7
MF:
C10H12O
Structure:
Chemical Name:
trans,trans-2,4-Heptadienal
CAS:
4313-03-5
MF:
C7H10O
Structure:
Chemical Name:
METHYL MYRISTATE
CAS:
124-10-7
MF:
C15H30O2
Structure:
Chemical Name:
2,4-Dimethylthiazole
CAS:
541-58-2
MF:
C5H7NS
Structure:
Chemical Name:
3,4-Hexanedione
CAS:
4437-51-8
MF:
C6H10O2
Structure:
Chemical Name:
2-Heptanol
CAS:
543-49-7
MF:
C7H16O
Structure:
Chemical Name:
1-Penten-3-ol
CAS:
616-25-1
MF:
C5H10O
Structure:
Chemical Name:
ETHYL (METHYLTHIO)ACETATE
CAS:
4455-13-4
MF:
C5H10O2S
Structure:
Chemical Name:
Isobutyric acid
CAS:
79-31-2
MF:
C4H8O2
Structure:
Chemical Name:
2-Methyl-2-pentenoic acid
CAS:
3142-72-1
MF:
C6H10O2
Structure:
Chemical Name:
Octyl 4-methoxycinnamate
CAS:
5466-77-3
MF:
C18H26O3
Structure:
Chemical Name:
2,6-Dimethyl-5-heptenal
CAS:
106-72-9
MF:
C9H16O
Structure:
Chemical Name:
2,4-Dimethyl-3-ethyl-1H-pyrrole
CAS:
517-22-6
MF:
C8H13N
Structure:
Chemical Name:
4-Methyloctanoic acid
CAS:
54947-74-9
MF:
C9H18O2
Structure:
Chemical Name:
2,6-DIMETHYLTHIOPHENOL
CAS:
118-72-9
MF:
C8H10S
Structure:
Chemical Name:
Piperidine
CAS:
110-89-4
MF:
C5H11N
Structure:
Chemical Name:
2,5-Dihydroxy-1,4-dithiane
CAS:
40018-26-6
MF:
C4H8O2S2
Structure:
Chemical Name:
2-Pentylpyridine
CAS:
2294-76-0
MF:
C10H15N
Structure:
Chemical Name:
γ-Valerolactone
CAS:
108-29-2
MF:
C5H8O2
Structure:
Chemical Name:
Diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate
CAS:
2436-79-5
MF:
C12H17NO4
Structure:
Chemical Name:
3-Acetyl-2,5-dimethylthiophene
CAS:
2530-10-1
MF:
C8H10OS
Structure:
Chemical Name:
gamma-Octanoic lactone
CAS:
104-50-7
MF:
C8H14O2
Structure:
Chemical Name:
2-Pentyl-3-methyl-2-cyclopenten-1-one
CAS:
1128-08-1
MF:
C11H18O
Structure:
Chemical Name:
4-Heptanone
CAS:
123-19-3
MF:
C7H14O
Structure:
Chemical Name:
(E,E)-Farnesol
CAS:
106-28-5
MF:
C15H26O
Structure:
Chemical Name:
Ethyl 3-phenylpropionate
CAS:
2021-28-5
MF:
C11H14O2
Structure:
Chemical Name:
2-Octanone
CAS:
111-13-7
MF:
C8H16O
Structure:
Chemical Name:
2',5'-Dimethoxyacetophenone
CAS:
1201-38-3
MF:
C10H12O3
Structure:
Chemical Name:
2,6-Diacetylpyridine
CAS:
1129-30-2
MF:
C9H9NO2
Structure:
Chemical Name:
1-Octen-3-ol
CAS:
3391-86-4
MF:
C8H16O
Structure:
Chemical Name:
Ethyl crotonate
CAS:
623-70-1
MF:
C6H10O2
Structure:
Chemical Name:
Pyruvic acid
CAS:
127-17-3
MF:
C3H4O3
Structure:
Chemical Name:
2-Acetylthiophene
CAS:
88-15-3
MF:
C6H6OS
Structure:
Chemical Name:
4-Methyl-5-vinylthiazole
CAS:
1759-28-0
MF:
C6H7NS
Structure:
Chemical Name:
2-Tridecanone
CAS:
593-08-8
MF:
C13H26O
Structure:
Chemical Name:
2-Methyl-1-butanol
CAS:
137-32-6
MF:
C5H12O
Structure:
Chemical Name:
4-Methyl-5-thiazolylethyl acetate
CAS:
656-53-1
MF:
C8H11NO2S
Structure:
Chemical Name:
2,5-Dimethyl-3(2H)-furanone
CAS:
14400-67-0
MF:
C6H8O2
Structure:
Chemical Name:
Tributyrin
CAS:
60-01-5
MF:
C15H26O6
Structure:
Chemical Name:
2,3-Pentanedione
CAS:
600-14-6
MF:
C5H8O2
Structure:
Chemical Name:
Butyl hexanoate
CAS:
626-82-4
MF:
C10H20O2
Structure:
Chemical Name:
2,5-Dimethylthiophene
CAS:
638-02-8
MF:
C6H8S
Structure:
Chemical Name:
3-Phenylpropionic acid
CAS:
501-52-0
MF:
C9H10O2
Structure:
Chemical Name:
5-Hydroxymethylfurfural
CAS:
67-47-0
MF:
C6H6O3
Structure:
Chemical Name:
1-Bromopentane
CAS:
110-53-2
MF:
C5H11Br
Structure:
Chemical Name:
2-Isobutylthiazole
CAS:
18640-74-9
MF:
C7H11NS
Structure:
Chemical Name:
trans-2-Hexen-1-ol
CAS:
928-95-0
MF:
C6H12O
Structure:
Chemical Name:
β-Lonone
CAS:
79-77-6
MF:
C13H20O
Structure:
Chemical Name:
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
CAS:
28664-35-9
MF:
C6H8O3
Structure:
Chemical Name:
1,1-Dimethoxyethane
CAS:
534-15-6
MF:
C4H10O2
Structure:
Chemical Name:
L-Menthyl acetate
CAS:
2623-23-6
MF:
C12H22O2
Structure:
Chemical Name:
2-Acetylpyridine
CAS:
1122-62-9
MF:
C7H7NO
Structure:
Chemical Name:
1-Pentanol
CAS:
71-41-0
MF:
C5H12O
Structure:
Chemical Name:
2-Methyl-2-thiazoline
CAS:
2346-00-1
MF:
C4H7NS
Structure:
Chemical Name:
Dihydro-2-methyl-3(2H)-thiophenone
CAS:
13679-85-1
MF:
C5H8OS
Structure:
Chemical Name:
D(+)-Carvone
CAS:
2244-16-8
MF:
C10H14O
Structure:
Chemical Name:
delta-Dodecalactone
CAS:
713-95-1
MF:
C12H22O2
Structure:
Chemical Name:
Ethyl L(-)-lactate
CAS:
687-47-8
MF:
C5H10O3
Structure:
Chemical Name:
5,6,7,8-Tetrahydroquinoxaline
CAS:
34413-35-9
MF:
C8H10N2
Structure:
Chemical Name:
Quinaldine
CAS:
91-63-4
MF:
C10H9N