Alcohols spices Phenols, ethers and epoxides Halogen, sulfur, nitrogen compounds Oxygen-containing heterocyclic compounds Aldehydes spices Macrocyclic musks Carboxylic acids and esters carbonyl spices Hydrocarbon spices Ketones spices Thiols spices Thioethers spices Pyrazine spices Aromatic acid, ester and derivatives
ChemicalBook >   Product Catalog >  Flavors and fragrances >  Synthetic fragrances

Synthetic fragrances

Alcohols spices Phenols, ethers and epoxides Halogen, sulfur, nitrogen compounds Oxygen-containing heterocyclic compounds Aldehydes spices Macrocyclic musks Carboxylic acids and esters carbonyl spices Hydrocarbon spices Ketones spices Thiols spices Thioethers spices Pyrazine spices Aromatic acid, ester and derivatives
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Synthetic fragrances is also known as artificially synthetic fragrance. It is a mimic of the natural flavors manufactured using science and technology by human beings. It refers to a “single-one” spice manufactured or prepared through chemical or biological pathways using different raw materials. Currently, there are already 5000 kinds of Synthetic fragrances in the world with 400 kinds of them belonging to commonly used products. Synthetic fragrances industry has become an important part of fine organic chemical industry.

Synthetic fragrances, according to their chemical structure or functional groups, can be divided into hydrocarbons, alcohols, acids, esters, lactones, aldehydes, ketones, phenols, ethers, acetals, ketals, shiff base, nitrile, macrocyclic, polycyclic, heterocyclic (pyrazine, pyridine, furan furosemide thiazole, etc.), sulfides, halides and so on.

The GB2760 in China allows the application of more than 257 kinds of Synthetic fragrances in the food flavors directories. The commonly used Synthetic fragrances in the beverage can be divided into esters and non-esters, two kinds.
(1) Synthetic esters spices: the esters of organic acids and alcohols, due to undergoing alkali saponification, generally have poor alkali resistance except the third class terpene alcohol esters (terpinyl acetate, linalyl acetate). The esters spices are generally prepared through the esterification of organic acids and alcohols. Among the esters spices listed in Table 1-4-21, acetate esters occupy the majority, up to 12 species. From the component of the alcohol, the number of alcohol ester is 11; the number of iso-amyl alcohol esters is 7; the number of methyl ester is 5. These kinds of esters are all difficultly soluble or almost insoluble in water, but being easily soluble in alcohol and ether. Owing to the highly volatility, it must be sealed and stored in a cool dark place. These esters spices are rarely used alone and are generally blended with a variety of other spices for application.
(2) Non-ester spices are mainly spices including alcohols, aldehydes, volatile acids, and ketones that exclude ester spices, wherein the aldehyde, the phenol and structure having unstable double bond occupies the majority of them. They can be easily oxidized in the air and should be given full attention.
In particular, the aromatic aldehydes that can have cannizarro reaction such as anisaldehyde, vanillin, ethyl vanillin, benzaldehyde, pepper aldehyde and aldehyde having double bond nearly to the aldehyde group (α- amyl cinnamaldehyde, cinnamic aldehyde and citral) are non-unstable esters spices. They are rarely used alone except vanillin and menthol with being blended with other spices for application in most cases.

Artificial spices are flavor components that have not been identified in the natural product (no matter whether or not processed) for human consumption. Such spices have fewer varieties with all of them manufactured by chemical methods, and their chemical structures have not yet been found in nature.
Based on this, the safety of these spices has drawn a lot of attention. In China, those spices included in the GB/T14156-93 "edible spices and coding" all have undergone certain toxicological evaluation, and are considered harmless to humans (in certain doses). Among them, except individual spices undergoing adequate toxicological evaluation, they are all currently classified as temporary license. It should be noted that, with the continuous development of science and technology and human awareness, some varieties originally belonging to artificial spice varieties have also found in some natural foods, thus being classified as nature-identical flavors. For example, the artificial spice, allyl caproate, temporarily used in China is now re-classified as nature-identical spice internationally.

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Structure:
Chemical Name:
2,4-HEPTADIEN-1-OL
CAS:
33467-79-7
MF:
C7H12O
Structure:
Chemical Name:
4-Mercapto-4-methylpentan-2-one
CAS:
19872-52-7
MF:
C6H12OS
Structure:
Chemical Name:
3-Bromocinnamic acid
CAS:
32862-97-8
MF:
C9H7BrO2
Structure:
Chemical Name:
3-ACETOXY-2-BUTANONE
CAS:
4906-24-5
MF:
C6H10O3
Structure:
Chemical Name:
Ambroxane
CAS:
6790-58-5
MF:
C16H28O
Structure:
Chemical Name:
CASHMERAN
CAS:
33704-61-9
MF:
C14H22O
Structure:
Chemical Name:
3-Phenylpropionic acid methyl ester
CAS:
103-25-3
MF:
C10H12O2
Structure:
Chemical Name:
CYCLOHEXYL PROPIONATE
CAS:
6222-35-1
MF:
C9H16O2
Structure:
Chemical Name:
N-BUTYL CINNAMATE
CAS:
538-65-8
MF:
C13H16O2
Structure:
Chemical Name:
DIHYDROTERPINEOL
CAS:
498-81-7
MF:
C10H20O
Structure:
Chemical Name:
2-Fluorocinnamic acid
CAS:
451-69-4
MF:
C9H7FO2
Structure:
Chemical Name:
CIS-4-DECENAL
CAS:
21662-09-9
MF:
C10H18O
Structure:
Chemical Name:
Isobutyl anthranilate
CAS:
7779-77-3
MF:
C11H15NO2
Structure:
Chemical Name:
2-PROPIONYLTHIAZOLE
CAS:
43039-98-1
MF:
C6H7NOS
Structure:
Chemical Name:
BUTYL PHENYLACETATE
CAS:
122-43-0
MF:
C12H16O2
Structure:
Chemical Name:
FEMA 3699
CAS:
66576-71-4
MF:
C8H16O2
Structure:
Chemical Name:
Allyl (3-methylbutoxy)acetate
CAS:
67634-00-8
MF:
C10H18O3
Structure:
Chemical Name:
LAURIC ACID ISOBUTYL ESTER
CAS:
37811-72-6
MF:
C16H32O2
Structure:
Chemical Name:
5-METHYL-3-HEXEN-2-ONE
CAS:
5166-53-0
MF:
C7H12O
Structure:
Chemical Name:
Amyl salicylate
CAS:
2050-08-0
MF:
C12H16O3
Structure:
Chemical Name:
trans-2-Methyl-2-pentenoic acid
CAS:
16957-70-3
MF:
C6H10O2
Structure:
Chemical Name:
4-AMINOBENZOIC ACID ISOBUTYL ESTER
CAS:
94-14-4
MF:
C11H15NO2
Structure:
Chemical Name:
4-isopropylcyclohexanol
CAS:
4621-04-9
MF:
C9H18O
Structure:
Chemical Name:
Dihydroactinidiolide
CAS:
17092-92-1
MF:
C11H16O2
Structure:
Chemical Name:
2,4,5-TRIMETHYL-3-OXAZOLINE
CAS:
22694-96-8
MF:
C6H11NO
Structure:
Chemical Name:
1,2-Butanedithiol
CAS:
16128-68-0
MF:
C4H10S2
Structure:
Chemical Name:
3-HEPTEN-2-ONE
CAS:
1119-44-4
MF:
C7H12O
Structure:
Chemical Name:
3-OCTANOL
CAS:
20296-29-1
MF:
C8H18O
Structure:
Chemical Name:
TRANS,TRANS-2,4-HEPTADIENAL
CAS:
5910-85-0
MF:
C7H10O
Structure:
Chemical Name:
(2-Methoxyethyl)benzene
CAS:
3558-60-9
MF:
C9H12O
Structure:
Chemical Name:
3-(Methylthio)propyl acetate
CAS:
16630-55-0
MF:
C6H12O2S
Structure:
Chemical Name:
2-Nonenal
CAS:
2463-53-8
MF:
C9H16O
Structure:
Chemical Name:
1,2,3,6-Tetrahydro-4-phenyl-pyridine
CAS:
10338-69-9
MF:
C11H13N
Structure:
Chemical Name:
2-N-HEXYLCYCLOPENTANONE
CAS:
13074-65-2
MF:
C11H20O
Structure:
Chemical Name:
CIS-3-HEXENYL ANTHRANILATE
CAS:
65405-76-7
MF:
C13H17NO2
Structure:
Chemical Name:
3,5-DIMETHYL-2-ETHYLPYRAZINE
CAS:
13925-07-0
MF:
C8H12N2
Structure:
Chemical Name:
1-METHYLTHIO-2-PROPANONE
CAS:
14109-72-9
MF:
C4H8OS
Structure:
Chemical Name:
2-Pentanethiol
CAS:
2084-19-7
MF:
C5H12S
Structure:
Chemical Name:
2-Ethyl-5-methylpyrazine
CAS:
13360-64-0
MF:
C7H10N2
Structure:
Chemical Name:
2-ISOPROPYLPYRAZINE
CAS:
29460-90-0
MF:
C7H10N2
Structure:
Chemical Name:
ALLYL BUTYRATE
CAS:
2051-78-7
MF:
C7H12O2
Structure:
Chemical Name:
3,4,5-Trimethoxycinnamic acid
CAS:
90-50-6
MF:
C12H14O5
Structure:
Chemical Name:
JasMonyl
CAS:
1322-17-4
MF:
C11H22O3
Structure:
Chemical Name:
Isophorone oxide
CAS:
10276-21-8
MF:
C9H14O2
Structure:
Chemical Name:
CIS-4-HEPTENAL
CAS:
6728-31-0
MF:
C7H12O
Structure:
Chemical Name:
trans,trans-2,4-Undecadienal
CAS:
30361-29-6
MF:
C11H18O
Structure:
Chemical Name:
3-CARENE
CAS:
13466-78-9
MF:
C10H16
Structure:
Chemical Name:
BENZYL ISOVALERATE
CAS:
103-38-8
MF:
C12H16O2
Structure:
Chemical Name:
P-TOLYL ISOBUTYRATE
CAS:
103-93-5
MF:
C11H14O2
Structure:
Chemical Name:
TRANS-2-HEXENYL BUTYRATE
CAS:
53398-83-7
MF:
C10H18O2
Structure:
Chemical Name:
FEMA 2079
CAS:
638-25-5
MF:
C13H26O2
Structure:
Chemical Name:
BUTYL VALERATE
CAS:
591-68-4
MF:
C9H18O2
Structure:
Chemical Name:
BENZYL BUTYL ETHER
CAS:
588-67-0
MF:
C11H16O
Structure:
Chemical Name:
Methyl allyl trisulfide
CAS:
34135-85-8
MF:
C4H8S3
Structure:
Chemical Name:
4-METHYLNONANOIC ACID
CAS:
45019-28-1
MF:
C10H20O2
Structure:
Chemical Name:
2-FURFURYL THIOPYRAZINE
CAS:
164352-93-6
MF:
C9H8N2OS
Structure:
Chemical Name:
2,6-Dimethyl-2-heptanol
CAS:
13254-34-7
MF:
C9H20O
Structure:
Chemical Name:
(S)-Isobutyl-2-chloropropanoate
CAS:
83261-15-8
MF:
C7H13ClO2
Structure:
Chemical Name:
3-Bromocinnamaldehyde
CAS:
97985-66-5
MF:
C9H7BrO
Structure:
Chemical Name:
3-Methoxycinnamic acid
CAS:
6099-04-3
MF:
C10H10O3
Structure:
Chemical Name:
7-BroMo-2-chlorobenzothiazole
CAS:
1188227-29-3
MF:
C7H3BrClNS
Structure:
Chemical Name:
3-Fluorocinnamic acid
CAS:
20595-30-6
MF:
C9H7FO2
Structure:
Chemical Name:
ALLYL FORMATE
CAS:
1838-59-1
MF:
C4H6O2
Structure:
Chemical Name:
ISOAMYL LAURATE
CAS:
6309-51-9
MF:
C17H34O2
Structure:
Chemical Name:
3-COUMARANONE
CAS:
7169-34-8
MF:
C8H6O2
Structure:
Chemical Name:
4-Hydroxy-3,5-dimethoxycinnamic acid
CAS:
530-59-6
MF:
C11H12O5
Structure:
Chemical Name:
1,4-Dithiane
CAS:
505-29-3
MF:
C4H8S2
Structure:
Chemical Name:
CITRONELLYL BUTYRATE
CAS:
141-16-2
MF:
C14H26O2
Structure:
Chemical Name:
1,1-Diethoxy-3,7-dimethylocta-2,6-diene
CAS:
7492-66-2
MF:
C14H26O2
Structure:
Chemical Name:
3-Chlorocinnamic acid
CAS:
1866-38-2
MF:
C9H7ClO2
Structure:
Chemical Name:
(+)-Fenchol
CAS:
2217-02-9
MF:
C10H18O
Structure:
Chemical Name:
1,3-DIPHENYL-2-BUTEN-1-ONE
CAS:
1322-90-3
MF:
C16H14O
Structure:
Chemical Name:
(+)-LONGIFOLENE
CAS:
475-20-7
MF:
C15H24
Structure:
Chemical Name:
3-(2-Furyl)acrylic acid
CAS:
539-47-9
MF:
C7H6O3
Structure:
Chemical Name:
ACETOACETIC ACID N-BUTYL ESTER
CAS:
591-60-6
MF:
C8H14O3
Structure:
Chemical Name:
Methyl 2-hexenoate
CAS:
2396-77-2
MF:
C7H12O2
Structure:
Chemical Name:
(+)-BETA-CEDRENE
CAS:
546-28-1
MF:
C15H24
Chemical Name:
Tricyclopentadiene
Structure:
Chemical Name:
CIS-3-HEXENYL CIS-3-HEXENOATE
CAS:
61444-38-0
MF:
C12H20O2
Structure:
Chemical Name:
Olean-12-en-28-oic acid, 3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-2,6,16,23-tetrahydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,4α,6β,16α)-
CAS:
144425-21-8
MF:
C63H102O33
Structure:
Chemical Name:
C-(4-BROMO-PYRIDIN-2-YL)-METHYLAMINE
CAS:
865156-50-9
MF:
C6H7BrN2
Structure:
Chemical Name:
trans-2-Nonen-1-ol
CAS:
31502-14-4
MF:
C9H18O
Structure:
Chemical Name:
2-METHYL-1-UNDECANOL
CAS:
10522-26-6
MF:
C12H26O
Structure:
Chemical Name:
Citronellyl nitrile
CAS:
51566-62-2
MF:
C10H17N
Structure:
Chemical Name:
4-Benzylpiperidine
CAS:
31252-42-3
MF:
C12H17N
Structure:
Chemical Name:
2-Iodo-4-nitroanisole
CAS:
5399-03-1
MF:
C7H6INO3
Structure:
Chemical Name:
2-FLUOROCINNAMALDEHYDE
CAS:
149733-71-1
MF:
C9H7FO
Structure:
Chemical Name:
2,4-DIMETHYL-3-CYCLOHEXENECARBOXALDEHYDE
CAS:
68039-49-6
MF:
C9H14O
Structure:
Chemical Name:
Lyral
CAS:
31906-04-4
MF:
C13H22O2
Structure:
Chemical Name:
2-Methylcinnamic acid
CAS:
2373-76-4
MF:
C10H10O2
Structure:
Chemical Name:
BENZYL TIGLATE
CAS:
37526-88-8
MF:
C12H14O2
Structure:
Chemical Name:
1-Acetylimidazole
CAS:
2466-76-4
MF:
C5H6N2O
Structure:
Chemical Name:
α-Bromocinnamaldehyde
CAS:
5443-49-2
MF:
C9H7BrO
Structure:
Chemical Name:
Diethyl malate
CAS:
7554-12-3
MF:
C8H14O5
Structure:
Chemical Name:
Neopentyl glycol diacrylate
CAS:
2223-82-7
MF:
C11H16O4
Structure:
Chemical Name:
Ethyl 2-trans-4-cis-decadienoate
CAS:
3025-30-7
MF:
C12H20O2
Structure:
Chemical Name:
TRANS,CIS-2,6-NONADIEN-1-OL
CAS:
28069-72-9
MF:
C9H16O
Structure:
Chemical Name:
Isooctyl acetate
CAS:
31565-19-2
MF:
C10H20O2
Structure:
Chemical Name:
N-(2-benzoyl-4-chlorophenyl)-2-chloro-N-methylacetamide
CAS:
6021-21-2
MF:
C16H13Cl2NO2
Chemical Name:
Para methyl acetophenone