Alcohols spices Phenols, ethers and epoxides Halogen, sulfur, nitrogen compounds Oxygen-containing heterocyclic compounds Aldehydes spices Macrocyclic musks Carboxylic acids and esters carbonyl spices Hydrocarbon spices Ketones spices Thiols spices Thioethers spices Pyrazine spices Aromatic acid, ester and derivatives
ChemicalBook >   Product Catalog >  Flavors and fragrances >  Synthetic fragrances

Synthetic fragrances

Alcohols spices Phenols, ethers and epoxides Halogen, sulfur, nitrogen compounds Oxygen-containing heterocyclic compounds Aldehydes spices Macrocyclic musks Carboxylic acids and esters carbonyl spices Hydrocarbon spices Ketones spices Thiols spices Thioethers spices Pyrazine spices Aromatic acid, ester and derivatives
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Synthetic fragrances is also known as artificially synthetic fragrance. It is a mimic of the natural flavors manufactured using science and technology by human beings. It refers to a “single-one” spice manufactured or prepared through chemical or biological pathways using different raw materials. Currently, there are already 5000 kinds of Synthetic fragrances in the world with 400 kinds of them belonging to commonly used products. Synthetic fragrances industry has become an important part of fine organic chemical industry.

Synthetic fragrances, according to their chemical structure or functional groups, can be divided into hydrocarbons, alcohols, acids, esters, lactones, aldehydes, ketones, phenols, ethers, acetals, ketals, shiff base, nitrile, macrocyclic, polycyclic, heterocyclic (pyrazine, pyridine, furan furosemide thiazole, etc.), sulfides, halides and so on.

The GB2760 in China allows the application of more than 257 kinds of Synthetic fragrances in the food flavors directories. The commonly used Synthetic fragrances in the beverage can be divided into esters and non-esters, two kinds.
(1) Synthetic esters spices: the esters of organic acids and alcohols, due to undergoing alkali saponification, generally have poor alkali resistance except the third class terpene alcohol esters (terpinyl acetate, linalyl acetate). The esters spices are generally prepared through the esterification of organic acids and alcohols. Among the esters spices listed in Table 1-4-21, acetate esters occupy the majority, up to 12 species. From the component of the alcohol, the number of alcohol ester is 11; the number of iso-amyl alcohol esters is 7; the number of methyl ester is 5. These kinds of esters are all difficultly soluble or almost insoluble in water, but being easily soluble in alcohol and ether. Owing to the highly volatility, it must be sealed and stored in a cool dark place. These esters spices are rarely used alone and are generally blended with a variety of other spices for application.
(2) Non-ester spices are mainly spices including alcohols, aldehydes, volatile acids, and ketones that exclude ester spices, wherein the aldehyde, the phenol and structure having unstable double bond occupies the majority of them. They can be easily oxidized in the air and should be given full attention.
In particular, the aromatic aldehydes that can have cannizarro reaction such as anisaldehyde, vanillin, ethyl vanillin, benzaldehyde, pepper aldehyde and aldehyde having double bond nearly to the aldehyde group (α- amyl cinnamaldehyde, cinnamic aldehyde and citral) are non-unstable esters spices. They are rarely used alone except vanillin and menthol with being blended with other spices for application in most cases.

Artificial spices are flavor components that have not been identified in the natural product (no matter whether or not processed) for human consumption. Such spices have fewer varieties with all of them manufactured by chemical methods, and their chemical structures have not yet been found in nature.
Based on this, the safety of these spices has drawn a lot of attention. In China, those spices included in the GB/T14156-93 "edible spices and coding" all have undergone certain toxicological evaluation, and are considered harmless to humans (in certain doses). Among them, except individual spices undergoing adequate toxicological evaluation, they are all currently classified as temporary license. It should be noted that, with the continuous development of science and technology and human awareness, some varieties originally belonging to artificial spice varieties have also found in some natural foods, thus being classified as nature-identical flavors. For example, the artificial spice, allyl caproate, temporarily used in China is now re-classified as nature-identical spice internationally.

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Structure:
Chemical Name:
2-ETHOXYCINNAMIC ACID
CAS:
69038-81-9
MF:
C11H12O3
Structure:
Chemical Name:
4-ETHYLPHENYLACETONE
CAS:
75251-24-0
MF:
C11H14O
Structure:
Chemical Name:
FEMA 2200
CAS:
7779-80-8
MF:
C11H22O2
Structure:
Chemical Name:
TOLUALDEHYDES
CAS:
1334-78-7
MF:
C7H6O
Structure:
Chemical Name:
3,4-(METHYLENEDIOXY)BENZYLIDENEACETONE
CAS:
3160-37-0
MF:
C11H10O3
Structure:
Chemical Name:
Indole-3-acetone
CAS:
1201-26-9
MF:
C11H11NO
Structure:
Chemical Name:
Ethyl 4-Hydroxyhydrocinnamate
CAS:
23795-02-0
MF:
C11H14O3
Structure:
Chemical Name:
Ethyl 4-methylcinnamate
CAS:
20511-20-0
MF:
C12H14O2
Structure:
Chemical Name:
2-ACETOXYCINNAMIC ACID
CAS:
55620-18-3
MF:
C11H10O4
Structure:
Chemical Name:
CINNAMYL PROPIONATE
CAS:
78761-38-3
MF:
C12H14O2
Structure:
Chemical Name:
1,4-Dithiane-2,5-Di(Methanethiol)
CAS:
136122-15-1
MF:
C6H12S4
Structure:
Chemical Name:
Vanillylidenacetone
CAS:
1080-12-2
MF:
C11H12O3
Structure:
Chemical Name:
2-(2-BUTYL)-4,5-DIMETHYL-3-THIAZOLINE
CAS:
65894-82-8
MF:
C9H17NS
Structure:
Chemical Name:
LINALYL ISOVALERATE
CAS:
1118-27-0
MF:
C15H26O2
Structure:
Chemical Name:
Dihydrocaffeic acid
CAS:
1078-61-1
MF:
C9H10O4
Structure:
Chemical Name:
3-TETRADECANONE
CAS:
629-23-2
MF:
C14H28O
Structure:
Chemical Name:
2-methylcyclopentenone
CAS:
1120-73-6
MF:
C6H8O
Structure:
Chemical Name:
3-[4-(Trifluoromethoxy)phenyl]acrylic acid
CAS:
783-13-1
MF:
C10H7F3O3
Structure:
Chemical Name:
ETHYL 2-METHYL-3-PENTENOATE
CAS:
1617-23-8
MF:
C8H14O2
Structure:
Chemical Name:
2-Methyl-4,5-dihydrofurane-3-thiol
CAS:
26486-13-5
MF:
C5H8OS
Structure:
Chemical Name:
2-Isopropylfuran
CAS:
10599-59-4
MF:
C7H10O
Structure:
Chemical Name:
2-BROMO-4-FLUOROCINNAMIC ACID
CAS:
289038-17-1
MF:
C9H6BrFO2
Structure:
Chemical Name:
2,4-Dimethylcinnamic acid
CAS:
1685-80-9
MF:
C11H12O2
Structure:
Chemical Name:
DIHYDROCARVEOL
CAS:
619-01-2
MF:
C10H18O
Structure:
Chemical Name:
2,3,4,5,6-PENTAFLUOROCINNAMIC ACID
CAS:
719-60-8
MF:
C9H3F5O2
Structure:
Chemical Name:
BETA-IONOL
CAS:
22029-76-1
MF:
C13H22O
Structure:
Chemical Name:
ETHYL 2-(METHYLDITHIO)PROPIONATE
CAS:
23747-43-5
MF:
C6H12O2S2
Structure:
Chemical Name:
2-CHLORO-5-NITROCINNAMIC ACID
CAS:
36015-19-7
MF:
C9H6ClNO4
Structure:
Chemical Name:
2-METHYL-3-(METHYLTHIO)PYRAZINE
CAS:
59021-03-3
MF:
C6H8N2S
Structure:
Chemical Name:
3-(TRIFLUOROMETHOXY)HYDROCINNAMIC ACID
CAS:
168833-77-0
MF:
C10H9F3O3
Structure:
Chemical Name:
4-FLUORO-3-METHOXYCINNAMIC ACID
CAS:
630424-79-2
MF:
C10H9FO3
Structure:
Chemical Name:
BUTYL ETHYL DISULPHIDE
CAS:
63986-03-8
MF:
C6H14S2
Structure:
Chemical Name:
TRICYCLODECENYL ACETATE
CAS:
5413-60-5
MF:
C12H16O2
Structure:
Chemical Name:
3-(4-PROPOXYPHENYL)ACRYLIC ACID
CAS:
69033-81-4
MF:
C12H14O3
Structure:
Chemical Name:
DIISOPROPYL TRISULFIDE
CAS:
5943-34-0
MF:
C6H14S3
Structure:
Chemical Name:
4-CHLORO-3,5-DINITRO-BENZOIC ACID ISOBUTYL ESTER
CAS:
58263-53-9
MF:
C11H11ClN2O6
Structure:
Chemical Name:
4-Chlorocinnamaldehyde
CAS:
49678-02-6
MF:
C9H7ClO
Structure:
Chemical Name:
2,4-NONADIEN-1-OL
CAS:
62488-56-6
MF:
C9H16O
Structure:
Chemical Name:
FEMA 2510
CAS:
10032-00-5
MF:
C14H22O3
Structure:
Chemical Name:
CARVONE
CAS:
99-49-0
MF:
C10H14O
Structure:
Chemical Name:
METHYL PENTYL DISULPHIDE
CAS:
72437-68-4
MF:
C6H14S2
Structure:
Chemical Name:
2-Isobutyl-4,6-dimethyldihydro-4H-1,3,5-dithiazine
CAS:
101517-87-7
MF:
C9H19NS2
Structure:
Chemical Name:
BENZYL METHYL DISULFIDE
CAS:
699-10-5
MF:
C8H10S2
Structure:
Chemical Name:
4-METHOXYCINNAMIC ACID
CAS:
943-89-5
MF:
C10H10O3
Structure:
Chemical Name:
FEMA 2689
MF:
C11H14O2
Structure:
Chemical Name:
4'-Chloro-2-phenylacetophenone
CAS:
1889-71-0
MF:
C14H11ClO
Structure:
Chemical Name:
DIHYDRO-BETA-IONONE
CAS:
17283-81-7
MF:
C13H22O
Structure:
Chemical Name:
Methyl 4-phenylbutanoate
CAS:
2046-17-5
MF:
C11H14O2
Structure:
Chemical Name:
Allyl Nonanoate
CAS:
7493-72-3
MF:
C12H22O2
Structure:
Chemical Name:
4-AMINOCINNAMIC ACID
CAS:
2393-18-2
MF:
C9H9NO2
Structure:
Chemical Name:
3,4-DIFLUOROHYDROCINNAMIC ACID
CAS:
161712-75-0
MF:
C9H8F2O2
Structure:
Chemical Name:
Borneol oil
CAS:
6627-72-1
MF:
C10H18O
Structure:
Chemical Name:
FEMA 2078
CAS:
7779-70-6
MF:
C14H28O2
Structure:
Chemical Name:
LIGNYL ACETATE
CAS:
128-51-8
MF:
C13H20O2
Structure:
Chemical Name:
DAMASCONE
CAS:
23726-91-2
MF:
C13H20O
Structure:
Chemical Name:
ISO-BUTYL-NONANOATE
CAS:
30982-03-7
MF:
C13H26O2
Structure:
Chemical Name:
Dinocap
CAS:
39300-45-3
MF:
C18H24N2O6
Structure:
Chemical Name:
Isobutyl isocyanate
CAS:
1873-29-6
MF:
C5H9NO
Structure:
Chemical Name:
Benzylthioacetate
CAS:
32362-99-5
MF:
C9H10OS
Structure:
Chemical Name:
3,5-Diisobutyl-1,2,4-trithiolane
CAS:
92900-67-9
MF:
C10H20S3
Structure:
Chemical Name:
(-)-PERILLALDEHYDE
CAS:
2111-75-3
MF:
C10H14O
Structure:
Chemical Name:
2-Mercaptopyrazine
CAS:
38521-06-1
MF:
C4H4N2S
Structure:
Chemical Name:
Dimethylisopropyldihydro-1,3,5-dithiazine
CAS:
104691-41-0
MF:
C8H17NS2
Structure:
Chemical Name:
2-BROMO-4,5-METHYLENEDIOXYCINNAMIC ACID
CAS:
27452-00-2
MF:
C10H7BrO4
Structure:
Chemical Name:
4-HYDROXY-3-METHOXYPHENYLACETONE
CAS:
2503-46-0
MF:
C10H12O3
Structure:
Chemical Name:
4-ACETAMIDOCINNAMIC ACID
CAS:
7152-04-7
MF:
C11H11NO3
Structure:
Chemical Name:
METHYL PAMPLEMOUSSE
CAS:
67674-46-8
MF:
C11H22O2
Structure:
Chemical Name:
4-CARBOXYCINNAMIC ACID
CAS:
19675-63-9
MF:
C10H8O4
Structure:
Chemical Name:
METHYL 2,5-DIHYDROXYCINNAMATE
CAS:
63177-57-1
MF:
C10H10O4
Structure:
Chemical Name:
FEMA 3332
CAS:
84642-61-5
MF:
C8H14O3
Structure:
Chemical Name:
ETHYL 3,5,5-TRIMETHYLHEXANOATE
CAS:
67707-75-9
MF:
C11H22O2
Structure:
Chemical Name:
1,2,3,4-Tetrahydropyridine
MF:
C5H9N
Structure:
Chemical Name:
2,3-Dihydro-5-methyl-4-[(2-methyl-3-furanyl)dithio]furan
CAS:
91265-97-3
MF:
C10H12O2S2
Structure:
Chemical Name:
2,3,5-TRIFLUOROCINNAMIC ACID
CAS:
237761-79-4
MF:
C9H5F3O2
Structure:
Chemical Name:
2,8-EPITHIO-P-MENTHANE
CAS:
68398-18-5
MF:
C10H18S
Structure:
Chemical Name:
5-BROMO-2-METHOXYCINNAMIC ACID
CAS:
40803-53-0
MF:
C10H9BrO3
Structure:
Chemical Name:
4,5-METHYLENEDIOXY-2-NITROCINNAMIC ACID
CAS:
6315-90-8
MF:
C10H7NO6
Structure:
Chemical Name:
4'-AMINOBUTYROPHENONE
CAS:
1688-71-7
MF:
C10H13NO
Structure:
Chemical Name:
3-[4-(BENZYLOXY)PHENYL]ACRYLIC ACID
CAS:
6272-45-3
MF:
C16H14O3
Structure:
Chemical Name:
7-OCTEN-2-OL, 2-METHYL-6-METHYLENE
CAS:
543-39-5
MF:
C10H18O
Structure:
Chemical Name:
7-CHLORO-2H-PYRIDO[3,2-B]-1,4-OXAZIN-3(4H)ONE
CAS:
205748-05-6
MF:
C7H5ClN2O2
Structure:
Chemical Name:
3-(ethyldithio)-2-methylfuran
CAS:
61197-07-7
MF:
C7H10OS2
Structure:
Chemical Name:
CINNAMIC ALCOHOL
MF:
C9H10O
Structure:
Chemical Name:
4'-METHYL-2-PHENYLACETOPHENONE
CAS:
2001-28-7
MF:
C15H14O
Structure:
Chemical Name:
7-BUTYL-2-OXEPANONE
CAS:
5579-78-2
MF:
C10H18O2
Structure:
Chemical Name:
10-OXAHEXADECANOLIDE
CAS:
1725-01-5
MF:
C15H28O3
Structure:
Chemical Name:
2-Bromocinnamic acid
CAS:
7499-56-1
MF:
C9H7BrO2
Structure:
Chemical Name:
4-CHLORO-3-(TRIFLUOROMETHYL)CINNAMIC ACID
CAS:
257872-87-0
MF:
C10H6ClF3O2
Structure:
Chemical Name:
Menthyl acetate
CAS:
89-48-5
MF:
C12H22O2
Structure:
Chemical Name:
4-FLUOROCINNAMIC ACID
CAS:
14290-86-9
MF:
C9H7FO2
Structure:
Chemical Name:
3-(4-CYCLOHEXYLBENZOYL)ACRYLIC ACID
CAS:
58897-74-8
MF:
C16H18O3
Structure:
Chemical Name:
2-BROMO-4,5-DIMETHOXYCINNAMIC ACID
CAS:
151539-52-5
MF:
C11H11BrO4
Structure:
Chemical Name:
HELIOTROPINE DIETHYL ACETAL
CAS:
40527-42-2
MF:
C12H16O4
Structure:
Chemical Name:
3-BROMO-4-HYDROXY-5-METHOXYCINNAMIC ACID
CAS:
6948-33-0
MF:
C10H9BrO4
Structure:
Chemical Name:
3-PROPYLBICYCLO(2.2.1)HEPT-5-ENE-2-CARBALDEHYDE
CAS:
39067-39-5
MF:
C11H16O
Structure:
Chemical Name:
ETHYL 2-METHYLPENTANOATE
CAS:
28959-02-6
MF:
C8H16O2
Structure:
Chemical Name:
3,4,5-TRIMETHOXYPHENYLACETONE
CAS:
16603-18-2
MF:
C12H16O4
Structure:
Chemical Name:
HEPTYL CINNAMATE
CAS:
10032-08-3
MF:
C16H22O2
Structure:
Chemical Name:
Delta Damascone
CAS:
57378-68-4
MF:
C13H20O
Structure:
Chemical Name:
2,3-Dimethoxycinnamic acid
CAS:
7461-60-1
MF:
C11H12O4