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METHYL 2,5-DIHYDROXYCINNAMATE

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METHYL 2,5-DIHYDROXYCINNAMATE Basic information

Product Name:
METHYL 2,5-DIHYDROXYCINNAMATE
Synonyms:
  • 2,5-DIHYDROXYMETHYLCINNAMATE
  • 2,5-DIHYDROXYCINNAMIC ACID METHYL ESTER
  • ERBSTATIN ANALOG
  • ERBSTATIN ANALOGUE
  • 3-(2,5-Dihydroxy-phenyl)-acrylicacidmethylester
  • METHYL 2,5-DIHYDROXYCINNAMATE
  • Erbstatin analog, Methyl 2,5-dihydroxycinnamate
  • Methyl 2,5-dihyroxycinnamate
CAS:
63177-57-1
MF:
C10H10O4
MW:
194.18
Product Categories:
  • Aromatic Cinnamic Acids, Esters and Derivatives
  • All Inhibitors
  • Inhibitors
  • Tyrosine Kinase Inhibitors
Mol File:
63177-57-1.mol
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METHYL 2,5-DIHYDROXYCINNAMATE Chemical Properties

Melting point:
178-180°C
Density 
1.318±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
0.1 M NaOH: soluble
form 
crystalline
color 
yellow
Water Solubility 
Soluble in methanol or 0.1M NaOH. Insoluble in water
CAS DataBase Reference
63177-57-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T
Risk Statements 
23/24/25-36/37/38
Safety Statements 
22-26-36-45
WGK Germany 
3
HS Code 
2918.29.7500
HazardClass 
6.1

MSDS

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METHYL 2,5-DIHYDROXYCINNAMATE Usage And Synthesis

Chemical Properties

Yellow-Brown Crystalline Powder

Uses

An inhibitor of the EGF receptor associated tyrosine kinase

Uses

A stable Erbstatin analogue that inhibits tyrosine kinase. Shown to delay the S-phase induction by epidermal growth factor in quiescent normal rat kidney cells, without affecting the total amount of DNA synthesis

Definition

ChEBI: 2,5-dihydroxycinnamic acid methyl ester is a cinnamate ester that is the methyl ester of 2,5-dihydroxycinnamic acid. It has a role as a human urinary metabolite, a plant metabolite, a geroprotector and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a cinnamate ester, a member of hydroquinones and a methyl ester.

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