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Dihydroactinidiolide

Basic information Biological activity Use Safety Supplier Related

Dihydroactinidiolide Basic information

Product Name:
Dihydroactinidiolide
Synonyms:
  • (2,6,6-TriMethyl-2-hydroxycyclohexylidene)acetic acid laCLone
  • 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-
  • 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (R)-
  • 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (S)-
  • Actinidiolide, dihydro-
  • dihydroactindiolide
  • (2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lacton
  • 2(4H)-Benzofuranone
CAS:
17092-92-1
MF:
C11H16O2
MW:
180.24
EINECS:
239-390-4
Product Categories:
  • ester Flavor
Mol File:
17092-92-1.mol
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Dihydroactinidiolide Chemical Properties

Melting point:
70-71°
alpha 
D24 -121.0° (c = 1.05 in CHCl3)
Boiling point:
296.1±9.0 °C(Predicted)
Density 
1.05±0.1 g/cm3(Predicted)
FEMA 
4020 | (+/-)-(2,6,6-TRIMETHYL-2-HYDROXYCYCLOHEXYLIDENE)ACETIC ACID GAMMA-LACTONE
storage temp. 
Sealed in dry,Room Temperature
Odor
musk coumarin
JECFA Number
1164
LogP
2.600
NIST Chemistry Reference
2(4H)-benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (r)-(17092-92-1)
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Safety Information

Safety Statements 
24/25
HS Code 
29329990
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Dihydroactinidiolide Usage And Synthesis

Biological activity

Dihydroactinidiolide is present in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression, and is also responsible for light adaptation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotection.

Use

Dihydroactinidiolide is an ester organic matter, which can be used as a food flavor.

Uses

Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, antibacterial activity, anticancer activity and neuroprotective effect[1]. Dihydroactinidiolide is also an inhibitor of AChE (IC50=34.03 nM) and has scavenging activities for DPPH and (.NO). Dihydroactinidiolide is present in plant leaves and fruits and is a potent plant growth inhibitor, regulator of gene expression, and responsible for light adaptation in Arabidopsis.

Definition

ChEBI: Dihydroactinidiolide is a member of benzofurans.

References

[1] Das M, et al. Dihydroactinidiolide, a natural product against Aβ25-35 induced toxicity in Neuro2a cells: Synthesis, in silico and in vitro studies. Bioorg Chem. 2018 Dec;81:340-349. DOI:10.1016/j.bioorg.2018.08.037
[2] Das M, et al. Dihydroactinidiolide, a natural product against Aβ25-35 induced toxicity in Neuro2a cells: Synthesis, in silico and in vitro studies. Bioorg Chem. 2018 Dec;81:340-349. DOI:10.1016/j.bioorg.2018.08.037

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