Alcohols spices Phenols, ethers and epoxides Halogen, sulfur, nitrogen compounds Oxygen-containing heterocyclic compounds Aldehydes spices Macrocyclic musks Carboxylic acids and esters carbonyl spices Hydrocarbon spices Ketones spices Thiols spices Thioethers spices Pyrazine spices Aromatic acid, ester and derivatives
ChemicalBook >   Product Catalog >  Flavors and fragrances >  Synthetic fragrances

Synthetic fragrances

Alcohols spices Phenols, ethers and epoxides Halogen, sulfur, nitrogen compounds Oxygen-containing heterocyclic compounds Aldehydes spices Macrocyclic musks Carboxylic acids and esters carbonyl spices Hydrocarbon spices Ketones spices Thiols spices Thioethers spices Pyrazine spices Aromatic acid, ester and derivatives
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Synthetic fragrances is also known as artificially synthetic fragrance. It is a mimic of the natural flavors manufactured using science and technology by human beings. It refers to a “single-one” spice manufactured or prepared through chemical or biological pathways using different raw materials. Currently, there are already 5000 kinds of Synthetic fragrances in the world with 400 kinds of them belonging to commonly used products. Synthetic fragrances industry has become an important part of fine organic chemical industry.

Synthetic fragrances, according to their chemical structure or functional groups, can be divided into hydrocarbons, alcohols, acids, esters, lactones, aldehydes, ketones, phenols, ethers, acetals, ketals, shiff base, nitrile, macrocyclic, polycyclic, heterocyclic (pyrazine, pyridine, furan furosemide thiazole, etc.), sulfides, halides and so on.

The GB2760 in China allows the application of more than 257 kinds of Synthetic fragrances in the food flavors directories. The commonly used Synthetic fragrances in the beverage can be divided into esters and non-esters, two kinds.
(1) Synthetic esters spices: the esters of organic acids and alcohols, due to undergoing alkali saponification, generally have poor alkali resistance except the third class terpene alcohol esters (terpinyl acetate, linalyl acetate). The esters spices are generally prepared through the esterification of organic acids and alcohols. Among the esters spices listed in Table 1-4-21, acetate esters occupy the majority, up to 12 species. From the component of the alcohol, the number of alcohol ester is 11; the number of iso-amyl alcohol esters is 7; the number of methyl ester is 5. These kinds of esters are all difficultly soluble or almost insoluble in water, but being easily soluble in alcohol and ether. Owing to the highly volatility, it must be sealed and stored in a cool dark place. These esters spices are rarely used alone and are generally blended with a variety of other spices for application.
(2) Non-ester spices are mainly spices including alcohols, aldehydes, volatile acids, and ketones that exclude ester spices, wherein the aldehyde, the phenol and structure having unstable double bond occupies the majority of them. They can be easily oxidized in the air and should be given full attention.
In particular, the aromatic aldehydes that can have cannizarro reaction such as anisaldehyde, vanillin, ethyl vanillin, benzaldehyde, pepper aldehyde and aldehyde having double bond nearly to the aldehyde group (α- amyl cinnamaldehyde, cinnamic aldehyde and citral) are non-unstable esters spices. They are rarely used alone except vanillin and menthol with being blended with other spices for application in most cases.

Artificial spices are flavor components that have not been identified in the natural product (no matter whether or not processed) for human consumption. Such spices have fewer varieties with all of them manufactured by chemical methods, and their chemical structures have not yet been found in nature.
Based on this, the safety of these spices has drawn a lot of attention. In China, those spices included in the GB/T14156-93 "edible spices and coding" all have undergone certain toxicological evaluation, and are considered harmless to humans (in certain doses). Among them, except individual spices undergoing adequate toxicological evaluation, they are all currently classified as temporary license. It should be noted that, with the continuous development of science and technology and human awareness, some varieties originally belonging to artificial spice varieties have also found in some natural foods, thus being classified as nature-identical flavors. For example, the artificial spice, allyl caproate, temporarily used in China is now re-classified as nature-identical spice internationally.

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Structure:
Chemical Name:
2-METHYLVALERIC ACID
CAS:
97-61-0
MF:
C6H12O2
Structure:
Chemical Name:
Leaf alcohol
CAS:
928-96-1
MF:
C6H12O
Structure:
Chemical Name:
Isoamyl o-hydroxybenzoate
CAS:
87-20-7
MF:
C12H16O3
Structure:
Chemical Name:
(+)-Isobutyl D-lactate
CAS:
61597-96-4
MF:
C7H14O3
Structure:
Chemical Name:
Cinnamyl propionate
CAS:
103-56-0
MF:
C12H14O2
Structure:
Chemical Name:
Hexyl benzoate
CAS:
6789-88-4
MF:
C13H18O2
Structure:
Chemical Name:
OCTYL BUTYRATE
CAS:
110-39-4
MF:
C12H24O2
Structure:
Chemical Name:
2-Pentylfuran
CAS:
3777-69-3
MF:
C9H14O
Structure:
Chemical Name:
ISOAMYL HEXANOATE
CAS:
2198-61-0
MF:
C11H22O2
Structure:
Chemical Name:
5-Hydroxy-4-octanone
CAS:
496-77-5
MF:
C8H16O2
Structure:
Chemical Name:
Ethanethioic acid S-ethyl ester
CAS:
625-60-5
MF:
C4H8OS
Structure:
Chemical Name:
Allicin
CAS:
539-86-6
MF:
C6H10OS2
Structure:
Chemical Name:
(E)-2-Octenal
CAS:
2548-87-0
MF:
C8H14O
Structure:
Chemical Name:
2-Furanacrolein
CAS:
623-30-3
MF:
C7H6O2
Structure:
Chemical Name:
2-Ethyl-4-methyl thiazole
CAS:
15679-12-6
MF:
C6H9NS
Structure:
Chemical Name:
Ethyl caprate
CAS:
110-38-3
MF:
C12H24O2
Structure:
Chemical Name:
2-Butanethiol
CAS:
513-53-1
MF:
C4H10S
Structure:
Chemical Name:
Estragole
CAS:
140-67-0
MF:
C10H12O
Structure:
Chemical Name:
2-Ethyl-3-methoxypyrazine
CAS:
25680-58-4
MF:
C7H10N2O
Structure:
Chemical Name:
(-)-PERILLALDEHYDE
CAS:
18031-40-8
MF:
C10H14O
Structure:
Chemical Name:
Methyl cedryl ether
CAS:
19870-74-7
MF:
C16H28O
Structure:
Chemical Name:
10-UNDECEN-1-OL
CAS:
112-43-6
MF:
C11H22O
Structure:
Chemical Name:
delta-Hexalactone
CAS:
823-22-3
MF:
C6H10O2
Structure:
Chemical Name:
2-Isopropyl-4-methyl thiazole
CAS:
15679-13-7
MF:
C7H11NS
Structure:
Chemical Name:
Methyl eugenol
CAS:
93-15-2
MF:
C11H14O2
Structure:
Chemical Name:
TRANS,TRANS-2,4-HEXADIEN-1-OL
CAS:
111-28-4
MF:
C6H10O
Structure:
Chemical Name:
2,2,2-Trichloro-1-phenylethyl acetate
CAS:
90-17-5
MF:
C10H9Cl3O2
Structure:
Chemical Name:
1-Octen-3-yl acetate
CAS:
2442-10-6
MF:
C10H18O2
Structure:
Chemical Name:
Isobutyl salicylate
CAS:
87-19-4
MF:
C11H14O3
Structure:
Chemical Name:
Dimethyl disulfide
CAS:
624-92-0
MF:
C2H6S2
Structure:
Chemical Name:
Methyl propionate
CAS:
554-12-1
MF:
C4H8O2
Structure:
Chemical Name:
METHYL 2,4-DIHYDROXY-3,6-DIMETHYLBENZOATE
CAS:
4707-47-5
MF:
C10H12O4
Structure:
Chemical Name:
Dodecyl methyl sulfide
CAS:
3698-89-3
MF:
C13H28S
Structure:
Chemical Name:
Bis(2-methyl-3-furyl)disulfide
CAS:
28588-75-2
MF:
C10H10O2S2
Structure:
Chemical Name:
NERYL ACETATE
CAS:
141-12-8
MF:
C12H20O2
Structure:
Chemical Name:
1,3-Dimercaptopropane
CAS:
109-80-8
MF:
C3H8S2
Structure:
Chemical Name:
3-(Trifluoromethyl)cinnamic acid
CAS:
779-89-5
MF:
C10H7F3O2
Structure:
Chemical Name:
ALLYL CINNAMATE
CAS:
1866-31-5
MF:
C12H12O2
Structure:
Chemical Name:
4,4'-Thiodibenzenethiol
CAS:
19362-77-7
MF:
C12H10S3
Structure:
Chemical Name:
Propyl cinnamate
CAS:
7778-83-8
MF:
C12H14O2
Structure:
Chemical Name:
Dibenzyl sulphide
CAS:
538-74-9
MF:
C14H14S
Structure:
Chemical Name:
2-Methylbenzenethiol
CAS:
137-06-4
MF:
C7H8S
Structure:
Chemical Name:
Ethyl furaneol
CAS:
27538-10-9
MF:
C7H10O3
Structure:
Chemical Name:
Styralyl acetate
CAS:
93-92-5
MF:
C10H12O2
Structure:
Chemical Name:
Benzyl acetate
CAS:
140-11-4
MF:
C9H10O2
Structure:
Chemical Name:
Diallyl sulfide
CAS:
592-88-1
MF:
C6H10S
Structure:
Chemical Name:
Citral
CAS:
5392-40-5
MF:
C10H16O
Structure:
Chemical Name:
Butyl butyrate
CAS:
109-21-7
MF:
C8H16O2
Structure:
Chemical Name:
Undecanal
CAS:
112-44-7
MF:
C11H22O
Structure:
Chemical Name:
5-Hydroxyoctanoic acid lactone
CAS:
698-76-0
MF:
C8H14O2
Structure:
Chemical Name:
1-Octen-3-one
CAS:
4312-99-6
MF:
C8H14O
Structure:
Chemical Name:
1-Benzyloxy-2-methoxy-4-propenylbenzene
CAS:
120-11-6
MF:
C17H18O2
Structure:
Chemical Name:
2-Hexylthiophene
CAS:
18794-77-9
MF:
C10H16S
Structure:
Chemical Name:
TETRAHYDROFURFURYL ACETATE
CAS:
637-64-9
MF:
C7H12O3
Structure:
Chemical Name:
2-(METHYLTHIO)THIAZOLE
CAS:
5053-24-7
MF:
C4H5NS2
Structure:
Chemical Name:
4-tert-Butylcyclohexyl acetate
CAS:
32210-23-4
MF:
C12H22O2
Structure:
Chemical Name:
2-Formamidothiazol-4-acetic acid
CAS:
75890-68-5
MF:
C6H6N2O3S
Structure:
Chemical Name:
Isoamyl cinnamate
CAS:
7779-65-9
MF:
C14H18O2
Structure:
Chemical Name:
TRANS-2-METHYL-2-BUTENAL
CAS:
497-03-0
MF:
C5H8O
Structure:
Chemical Name:
Hexyl hexanoate
CAS:
6378-65-0
MF:
C12H24O2
Structure:
Chemical Name:
Veratraldehyde
CAS:
120-14-9
MF:
C9H10O3
Structure:
Chemical Name:
2-Methyl-3-(methylthio)pyrazine
CAS:
2882-20-4
MF:
C6H8N2S
Structure:
Chemical Name:
Ethyl oleate
CAS:
111-62-6
MF:
C20H38O2
Structure:
Chemical Name:
2-Chloropyrazine
CAS:
14508-49-7
MF:
C4H3ClN2
Structure:
Chemical Name:
Phenethyl butyrate
CAS:
103-52-6
MF:
C12H16O2
Structure:
Chemical Name:
3-Methyl-2-butanethiol
CAS:
2084-18-6
MF:
C5H12S
Structure:
Chemical Name:
trans-Cinnamic acid
CAS:
140-10-3
MF:
C9H8O2
Structure:
Chemical Name:
Ethyl 3-hexenoate
CAS:
2396-83-0
MF:
C8H14O2
Structure:
Chemical Name:
2,4,5-TRIMETHYLANILINE
CAS:
94-48-4
MF:
C17H22O2
Structure:
Chemical Name:
2-Methyl-3-furanthiol
CAS:
28588-74-1
MF:
C5H6OS
Structure:
Chemical Name:
Propyl propionate
CAS:
106-36-5
MF:
C6H12O2
Structure:
Chemical Name:
9-DECENOIC ACID
CAS:
14436-32-9
MF:
C10H18O2
Structure:
Chemical Name:
ETHYL 2-METHYLPENTANOATE
CAS:
39255-32-8
MF:
C8H16O2
Structure:
Chemical Name:
Isobutyl isobutyrate
CAS:
97-85-8
MF:
C8H16O2
Structure:
Chemical Name:
2-Methoxy-3-sec-butyl pyrazine
CAS:
24168-70-5
MF:
C9H14N2O
Structure:
Chemical Name:
N-DECYL ACETATE
CAS:
112-17-4
MF:
C12H24O2
Structure:
Chemical Name:
3-Methylbutyl 3-methylbutanoate
CAS:
659-70-1
MF:
C10H20O2
Structure:
Chemical Name:
2-Propylpyrazine
CAS:
18138-03-9
MF:
C7H10N2
Structure:
Chemical Name:
Triacetin
CAS:
102-76-1
MF:
C9H14O6
Structure:
Chemical Name:
METHYL 2-NONYNOATE
CAS:
111-80-8
MF:
C10H16O2
Structure:
Chemical Name:
2-Methylbutyl 2-methylbutyrate
CAS:
2445-78-5
MF:
C10H20O2
Structure:
Chemical Name:
BUTYL LAURATE
CAS:
106-18-3
MF:
C16H32O2
Structure:
Chemical Name:
2-Acetyl pyrrole
CAS:
1072-83-9
MF:
C6H7NO
Structure:
Chemical Name:
2-HYDROXYTHIOANISOLE
CAS:
1073-29-6
MF:
C7H8OS
Structure:
Chemical Name:
FEMA 2871
CAS:
140-26-1
MF:
C13H18O2
Structure:
Chemical Name:
2,2,4,4,6,6-Hexamethyl-S-trithiane
CAS:
828-26-2
MF:
C9H18S3
Structure:
Chemical Name:
NEROL
CAS:
106-25-2
MF:
C10H18O
Structure:
Chemical Name:
Formic acid isopropyl ester
CAS:
625-55-8
MF:
C4H8O2
Structure:
Chemical Name:
Benzyl propionate
CAS:
122-63-4
MF:
C10H12O2
Structure:
Chemical Name:
4-(4-Methoxyphenyl)-2-butanone
CAS:
104-20-1
MF:
C11H14O2
Structure:
Chemical Name:
Benzyl formate
CAS:
104-57-4
MF:
C8H8O2
Structure:
Chemical Name:
2-Methyl butyric acid
CAS:
116-53-0
MF:
C5H10O2
Structure:
Chemical Name:
Isobutyl 5-chloro-2,2-dimethylvalerate
CAS:
109232-37-3
MF:
C11H21ClO2
Structure:
Chemical Name:
Ethyl myristate
CAS:
124-06-1
MF:
C16H32O2
Structure:
Chemical Name:
Ethyl laurate
CAS:
106-33-2
MF:
C14H28O2
Structure:
Chemical Name:
Phenylacetaldehyde
CAS:
122-78-1
MF:
C8H8O
Structure:
Chemical Name:
3-Methyl-1-butanethiol
CAS:
541-31-1
MF:
C5H12S
Structure:
Chemical Name:
cis-3-Hexenyl benzoate
CAS:
25152-85-6
MF:
C13H16O2
Structure:
Chemical Name:
3-ACETYL-2,5-DIMETHYLFURAN
CAS:
10599-70-9
MF:
C8H10O2
Structure:
Chemical Name:
4-Methoxycinnamic acid
CAS:
830-09-1
MF:
C10H10O3