Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Flavors and fragrances >  Synthetic fragrances >  Oxygen-containing heterocyclic compounds >  Thiazole, thiophene, and pyridine >  Quinaldine

Quinaldine

Basic information Safety Supplier Related

Quinaldine Basic information

Product Name:
Quinaldine
Synonyms:
  • 2-Methylchinolin
  • 2-Methylpuinoiline
  • QUINALDINE MINIMUM 90% (GC)
  • QUINALDINE 98+%
  • QUINALDINE MIN 96%
  • Quinaldine,~91%
  • Quinaldine97%
  • 2- Methyl Quinoline (Quinaldine)
CAS:
91-63-4
MF:
C10H9N
MW:
143.19
EINECS:
202-085-1
Product Categories:
  • Alkylquinolines
  • Quinolines
  • Quinoline&Isoquinoline
  • Quinoline
  • Quinoline Derivertives
  • Flavor
  • Intermediates of Dyes and Pigments
Mol File:
91-63-4.mol
More
Less

Quinaldine Chemical Properties

Melting point:
-2 °C
Boiling point:
248 °C
Density 
1.058 g/mL at 25 °C(lit.)
vapor pressure 
<0.1 hPa (20 °C)
refractive index 
n20/D 1.612(lit.)
Flash point:
175 °F
storage temp. 
Store below +30°C.
solubility 
chloroform: soluble(lit.)
pka
5.83(at 20℃)
form 
Crystalline Powder
color 
White to slightly yellow
PH
6.9 (H2O, 20℃)(saturated aqueous solution)
Water Solubility 
PRACTICALLY INSOLUBLE
Sensitive 
Light Sensitive
Merck 
14,8047
BRN 
110309
Stability:
Stable, but may be light sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference
91-63-4(CAS DataBase Reference)
NIST Chemistry Reference
Quinoline, 2-methyl-(91-63-4)
EPA Substance Registry System
Quinaldine (91-63-4)
More
Less

Safety Information

Hazard Codes 
Xn
Risk Statements 
21/22-68-36/37/38
Safety Statements 
36-45-36/37/39-26
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
RTECS 
UZ9625000
8-23
TSCA 
Yes
HS Code 
29334990
Toxicity
LD50 orally in rats: 1.23 g/kg (Smyth)

MSDS

More
Less

Quinaldine Usage And Synthesis

Chemical Properties

Quinaldine or 2-methylquinoline is an organic compound with the formula CH3C9H6N. It is one of the methyl derivative of a heterocyclic compound quinoline. It is bioactive and is used in the preparation of various dyes. It is a colorless oil but commercial samples can appear colored.

Uses

Quinaldine is an anaesthetic used in fish transportation. Also used in anti-malaria drugs, in manufacturing dyes, food colorants , pharmaceuticals and pH indicators.

Definition

ChEBI: A quinoline compound in which the quinoline skeleton is substituted at C-2 with a methyl group.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 13, p. 1279, 1976 DOI: 10.1002/jhet.5570130626
The Journal of Organic Chemistry, 52, p. 3847, 1987 DOI: 10.1021/jo00226a023
Synthesis, p. 324, 1996 DOI: 10.1055/s-1996-4221

General Description

A colorless oily liquid darkening to red-brown on exposure to air. Flash point 175°F. Denser than water and slightly soluble in water. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. Used to make dyes, pharmaceuticals and other chemicals.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Quinaldine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. Keep tightly closed and protected from light .

Hazard

Strong irritant to mucous membranes.

Fire Hazard

Quinaldine is probably combustible.

Purification Methods

Dry it with Na2SO4 or by refluxing with BaO, then fractionally distil it under reduced pressure and redistil it from zinc dust. Purify it further by conversion to its phosphate (m 220o) or picrate (m 192o) from which after recrystallisation, the free base is regenerated. [Packer et al. J Am Chem Soc 80 905 1958.] Its ZnCl2 complex can be used for the same purpose. [Beilstein 20 III/IV 3454, 20 V 375.]

Quinaldine Preparation Products And Raw materials

Raw materials

Preparation Products

QuinaldineSupplier

Tocopharm Co., Ltd. Gold
Tel
021-69895597- ;021-69895597- ;021-69895597-
Email
info@tocopharm.com;sales@tocopharm.com;739486509@qq.com
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Email
sh@meryer.com
Alfa Aesar
Tel
400-610-6006; 021-67582000
Email
saleschina@alfa-asia.com
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Email
Sales-CN@TCIchemicals.com