Quinaldic acid Chemical Properties

Melting point:

156-158 °C (lit.)

Boiling point:

247-250

Density 

1.2427 (rough estimate)

refractive index 

1.5200 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

14g/l

form 

Needle-Like Crystalline Powder

pka

1.20±0.30(Predicted)

color 

Light brown

PH

3.0-3.5 (10g/l, H2O, 20℃)

Water Solubility 

soluble

Merck 

14,8046

BRN 

126322

CAS DataBase Reference

93-10-7(CAS DataBase Reference)

NIST Chemistry Reference

2-Quinolinecarboxylic acid(93-10-7)

EPA Substance Registry System

2-Quinolinecarboxylic acid (93-10-7)

Safety Information

Hazard Codes 

Xi,T

Risk Statements 

36/37/38-23/24/25

Safety Statements 

26-36-37/39-45-36/37/39

WGK Germany 

3

RTECS 

UZ9100000

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29334990

MSDS

• Language:English Provider:2-Quinolinecarboxylic acid
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Quinaldic acid Usage And Synthesis

Chemical Properties

light brown needle-like crystalline powder

Uses

2-?Quinolinecarboxylic acid can be found in the studying of ligands for the purpose of copper-catalyzed Ullmann reactions with aryl ethers and aryl iodides.

Uses

For the determination of copper, zinc and uranium with which it forms insoluble salts.

Definition

ChEBI: A quinolinemonocarboxylic acid having the carboxy group at the 2-position.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1840, 1946 DOI: 10.1021/ja01213a045

General Description

Quinaldic acid is also referred as quinoline-2-carboxylic acid. Microwave-assisted preparation of substituted anilides of quinaldic acid has been reported. It inhibits the oxidation of pyruvate, α-ketoglutarate, glutamate and citrate in rat liver mitochondria. Quinaldic acid is a metabolite of tryptophan degradation and inhibits the gluconeogenesis in perfused livers.

Purification Methods

Crystallise quinaldic acid from *C6H6 or AcOH. It is used for the estimation of many metals. The methyl ester has m 86-87o (from hexane) and pK25 1.76. [Chauduri et al. Frez Z Anal Chem 281 361 1976, Beilstein 22 H 71, 22 II 55, 22 III/IV 1149, 22/3 V 183.]

Quinaldic acid(93-10-7)Related Product Information

• Citric acid
• Quinaldine
• 8-Hydroxyquinaldine
• 2,4-Dichlorobenzoic acid
• Folic acid
• 2,3,4-Trihydroxybenzoic acid
• Quinoline
• Quinclorac
• Nalidixic acid
• Quetiapine fumarate
• Ethyl 2-(Chlorosulfonyl)acetate
• Glycine
• Ethoxyquin
• 8-Aminoquinaldine
• Isoquinoline
• OXOLINIC ACID IMPURITY A
• QUINOLINE-4-CARBOXYLIC ACID
• QUINOXALINE-5-CARBOXYLIC ACID