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Quinolinic acid

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Quinolinic acid Basic information

Product Name:
Quinolinic acid
Synonyms:
  • 2,3-PyridinedicarboxylicAcid99%
  • QuinolinicAcid>99%
  • Pyridin-2,3-dicarbonsaeure
  • 2,3-Pyridinedicarboxylic
  • 2,3-PYRIDINEDICARBOXYLIC ACID (QUINOLINIC ACID)
  • 2,3-pyridine dicarbo
  • 2,3-PYRIDINEDICARBOXYLIC ACID
  • AKOS BBS-00003814
CAS:
89-00-9
MF:
C7H5NO4
MW:
167.12
EINECS:
201-874-8
Product Categories:
  • Pyridine series
  • Pyridine
  • pyridine derivative
  • Carboxylic Acids
  • Pyridines
  • Heterocyclic Compounds
  • Heterocycles
  • Inhibitors
  • Carboxylic Acids
  • Medical Intermediates
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Pesticides intermediate
  • Pyrimidines
Mol File:
89-00-9.mol
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Quinolinic acid Chemical Properties

Melting point:
188-190 °C (dec.)(lit.)
Boiling point:
295.67°C (rough estimate)
Density 
1.5216 (rough estimate)
refractive index 
1.6280 (estimate)
storage temp. 
Store at RT
solubility 
10g/l
pka
2.43(at 25℃)
form 
Crystalline Powder
color 
White to light yellow-beige
Water Solubility 
0.55 g/100 mL
Merck 
14,8073
BRN 
137110
InChIKey
GJAWHXHKYYXBSV-UHFFFAOYSA-N
CAS DataBase Reference
89-00-9(CAS DataBase Reference)
EPA Substance Registry System
2,3-Pyridinedicarboxylic acid (89-00-9)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38-33
Safety Statements 
26-36/37-24/25-37
WGK Germany 
3
RTECS 
US7967250
TSCA 
T
HazardClass 
IRRITANT
HS Code 
29333999
Hazardous Substances Data
89-00-9(Hazardous Substances Data)

MSDS

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Quinolinic acid Usage And Synthesis

Chemical Properties

White powder;Light yellow powder

Uses

Inhibits glucose synthesis

Uses

An inhibitor of glucose synthesis.

Uses

A matabolite of tryptophan and a putative NMDA receptor agonist.

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 3020, 1949 DOI: 10.1021/ja01177a021

Hazard

A poison by skin contact. Moderately toxic by ingestion. A mild skin irritant.

Industrial uses

The use of quinolinic acid during flotation of hematite results in the adsorption of quinoline on hematite, allowing amine to selectively adsorb onto the hematite surface.

Biological Activity

Endogenous NMDA agonist and transmitter candidate. May distinguish between NMDA receptor subtypes.

Safety Profile

A poison by skin contact. Moderately toxic by ingestion. Experimental reproductive effects. A mdd skinn irritant. When heated to decomposition it emits toxic vapors of NOx.

Quinolinic acid Preparation Products And Raw materials

Preparation Products

5-Methoxymethyl-2,3-pyridinedicarboxylic acid 3-Amino-2-pyridinecarboxylic acid3-TERT-BUTOXYCARBONYLAMINO-PYRIDINE-2-CARBOXYLIC ACID3-AMINO-6-BROMO-PYRIDIN-2-OLMETHYL 3-CYANOPYRIDINE-2-CARBOXYLATE3-CYANOPYRIDINE-2-CARBOXYLIC ACID3-CARBAMOYLPICOLINIC ACIDQUINOLINIMIDEMETHYL 3-(CHLOROCARBONYL)PYRIDINE-2-CARBOXYLATE HYDROCHLORIDE2-(AMINOCARBONYL)NICOTINIC ACID5-Methylpyridine-2,3-dicarboxylic acid3-(METHOXYCARBONYL)PYRIDINE-2-CARBOXYLIC ACID

Raw materials

EtanolPotassium permanganateQuinolineAcroleinDiethyl oxalacetate

Quinolinic acidSupplier

Alfa Aesar Gold
Tel
400-610-6006; 021-67582000
Email
saleschina@alfa-asia.com
Rare Chemistry (Hong Kong) Co., Ltd. Gold
Email
93634146@qq.com
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Email
sh@meryer.com
INTATRADE GmbH
Tel
+49 3493/605464
Email
sales@intatrade.de
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