3,5-Dimethoxybenzoic acid Chemical Properties

Melting point:

178-180 °C (lit.)

Boiling point:

275.56°C (rough estimate)

Density 

1.2481 (rough estimate)

refractive index 

1.4500 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

almost transparency in hot Methanol

pka

3.96±0.10(Predicted)

form 

Crystalline Powder

color 

Almost white to light beige-pink

BRN 

511834

InChIKey

IWPZKOJSYQZABD-UHFFFAOYSA-N

LogP

2.190

CAS DataBase Reference

1132-21-4(CAS DataBase Reference)

NIST Chemistry Reference

3,5-Dimethoxybenzoic acid(1132-21-4)

EPA Substance Registry System

Benzoic acid, 3,5-dimethoxy- (1132-21-4)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29189090

MSDS

• Language:English Provider:3,5-Dimethoxybenzoic acid
• Language:English Provider:SigmaAldrich
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3,5-Dimethoxybenzoic acid Usage And Synthesis

Chemical Properties

almost white to light beige-pink cryst. powder

Uses

3,5-Dimethoxybenzoic acid (3,5-DmeoxBA) can be used as a reactant for the synthesis of:

• 5,7-Dimethoxy-3,4-diphenylisocoumarin by coupling with diphenylacetylene.
• Biotin dimedone, a reagent used in the study of protein sulfenation.

It can also be used as a ligand to synthesize lanthanide complexes [Ln(3,5-DmeoxBA)₃(phen)]₂; where phen is 1,10-phenanthroline.

Definition

ChEBI: 3,5-dimethoxybenzoic acid is a methoxybenzoic acid that is benzoic acid which is substituted by methoxy groups at positions 3 and 5. It has a role as a plant metabolite. It is a conjugate acid of a 3,5-dimethoxybenzoate.

Purification Methods

Crystallise the acid from water, EtOH or aqueous acetic acid and dry it in a vacuum. [Beilstein 10 H 405, 10 I 195, 10 III 1446, 10 IV 1501.]

3,5-Dimethoxybenzoic acid(1132-21-4)Related Product Information

• 3-Methoxybenzoic acid
• 4-Aminobenzoic acid
• Dimethyldimethoxysilane
• 2-Methoxybenzoic acid
• Benzoic acid
• 4-Methoxybenzoic acid
• 4-Dimethylaminobenzoic acid
• Folic acid
• Ascoric Acid
• Methyl syringate
• Methyl 3,4,5-trimethoxybenzoate
• Methyl 2-amino-3,4,5-trimethoxybenzoate
• Syringic acid(4-Hydroxy 3,5-dimethoxybenzoic acid)
• 3,4,5-TRIETHOXYBENZOIC ACID
• Methyl 2-nitro-3,4,5-trimethoxybenzoate
• 3,4,5-Trimethoxy benzoic acid
• Reserpine
• Methyl 3,5-dimethoxybenzoate