HIPPURIC ACID SODIUM SALT
HIPPURIC ACID SODIUM SALT Basic information
- Product Name:
- HIPPURIC ACID SODIUM SALT
- Synonyms:
-
- n-benzoyl-glycinmonosodiumsalt
- N-BENZOYLGLYCINE SODIUM SALT
- Glycine,N-benzoyl-,monosodiumsalt
- hippuricacid,monosodiumsalt
- Glycine, N-benzoyl-,sodium salt (1:1)
- HIPPURIC ACID SODIUM SALT
- BENZOYLAMINOACETIC ACID SODIUM SALT
- BENZOYLAMINOACETIC SODIUM SALT
- CAS:
- 532-94-5
- MF:
- C9H10NNaO3
- MW:
- 203.17
- EINECS:
- 208-548-4
- Mol File:
- 532-94-5.mol
HIPPURIC ACID SODIUM SALT Chemical Properties
- Melting point:
- 240～244℃
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- H2O: 0.5 M at 20 °C, clear, colorless
- form
- Solid
- color
- White powder
- Water Solubility
- Soluble in water.
- BRN
- 3638470
- CAS DataBase Reference
- 532-94-5(CAS DataBase Reference)
- EPA Substance Registry System
- Glycine, N-benzoyl-, monosodium salt (532-94-5)
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 24/25-36/37-26-22
- WGK Germany
- 3
- RTECS
- MR8170000
- TSCA
- Yes
- HS Code
- 2924.29.9500
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
HIPPURIC ACID SODIUM SALT Usage And Synthesis
Chemical Properties
White crystalline powder
Uses
Hippuric Acid Sodium Salt can be used for agrobacterium-mediated rice genetic transformation method.
Biochem/physiol Actions
Hippuric acid is a low molecular weight phenolic carboxylic acid urinary metabolite that may be a useful urinary biomarker for certain cancers such as gastric cancer and oxidative stress.
in vivo
Sodium hippurate, 98% (Hippuric acid, 100 mg/kg; i.p.; five times per week; 10 weeks) promotes renal fibrosis and dysfunction in 5/6 nephrectomized rats[4].
Sodium hippurate, 98% (Hippuric acid, 10 mg/kg; p.o.; daily; 4 weeks) alleviates hyperuricemia in mice by promoting intestinal urate excretion via enhancing ABCG2-mediated transport[5].
Sodium hippurate, 98% (Hippuric acid, 50-150 mg/kg; p.o.; once daily; 7 days) alleviates DSS-induced colitis in male C57BL/6J mice, as shown by reduced clinical activity, improved intestinal barrier integrity, and modulated gut microbiota[6].
| Animal Model: | Male Sprague Dawley rats (7-week-old, weight not specified); 5/6 nephrectomy model[4] |
| Dosage: | 100 mg/kg |
| Administration: | Intraperitoneal injection, five times per week, for 10 weeks |
| Result: | Significantly increased levels of serum creatinine (SCr), blood urea nitrogen (BUN), and HA. Showed increased tubulointerstitial fibrosis and glomerulosclerosis, with larger COL1A1-, VIM-, and ACTA2-positive areas. Revealed lower NRF2 levels. Decreased activities of SOD, CAT, and GSH- Px. Increased MDA levels in the kidneys, indicating redox imbalance. |
IC 50
MMP9; Microbial Metabolite; Human Endogenous Metabolite
HIPPURIC ACID SODIUM SALT Preparation Products And Raw materials
Preparation Products
HIPPURIC ACID SODIUM SALTSupplier
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HIPPURIC ACID SODIUM SALT(532-94-5)Related Product Information
- Methotrexate
- N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt
- Sipatrigine
- P-AMINOHIPPURIC ACID SODIUM SALT
- 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT
- Methotrexate sodium
- Pemetrexed Disodium
- Hippuric acid
- URIC ACID SODIUM SALT
- HIPPURIC ACID SODIUM SALT
- HIPPURIC ACID SODIUM SALT
- Uric acid
- Sivelestat sodium
- o-Iodohippuricacidsodiumsaltdihydrate
- METHOTREXATE SODIUM SALT, [3',5',7'-3H]
- sodium folate
- HIPPURIC ACID SODIUM SALT HYDRATE
- FOLIC ACID, SODIUM SALT, [3,5,7,9-3H]