Basic information Safety Supplier Related

HIPPURIC ACID SODIUM SALT

Basic information Safety Supplier Related

HIPPURIC ACID SODIUM SALT Basic information

Product Name:
HIPPURIC ACID SODIUM SALT
Synonyms:
  • n-benzoyl-glycinmonosodiumsalt
  • N-BENZOYLGLYCINE SODIUM SALT
  • Glycine,N-benzoyl-,monosodiumsalt
  • hippuricacid,monosodiumsalt
  • Glycine, N-benzoyl-,sodium salt (1:1)
  • HIPPURIC ACID SODIUM SALT
  • BENZOYLAMINOACETIC ACID SODIUM SALT
  • BENZOYLAMINOACETIC SODIUM SALT
CAS:
532-94-5
MF:
C9H10NNaO3
MW:
203.17
EINECS:
208-548-4
Mol File:
532-94-5.mol
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HIPPURIC ACID SODIUM SALT Chemical Properties

Melting point:
240～244℃
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: 0.5 M at 20 °C, clear, colorless
form 
Solid
color 
White powder
Water Solubility 
Soluble in water.
BRN 
3638470
Major Application
detection
InChI
1S/C9H9NO3.Na.H2O/c11-8(12)6-10-9(13)7-4-2-1-3-5-7;;/h1-5H,6H2,(H,10,13)(H,11,12);;1H2/q;+1;/p-1
InChIKey
IOZRWVOSUXHESF-UHFFFAOYSA-M
SMILES
O.[Na+].[O-]C(=O)CNC(=O)c1ccccc1
CAS DataBase Reference
532-94-5(CAS DataBase Reference)
EPA Substance Registry System
Glycine, N-benzoyl-, monosodium salt (532-94-5)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
24/25-36/37-26-22
WGK Germany 
3
RTECS 
MR8170000
TSCA 
TSCA listed
HS Code 
2924.29.9500
Storage Class
11 - Combustible Solids

MSDS

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HIPPURIC ACID SODIUM SALT Usage And Synthesis

Chemical Properties

White crystalline powder

Uses

Hippuric Acid Sodium Salt can be used for agrobacterium-mediated rice genetic transformation method.

Biochem/physiol Actions

Hippuric acid is a low molecular weight phenolic carboxylic acid urinary metabolite that may be a useful urinary biomarker for certain cancers such as gastric cancer and oxidative stress.

in vivo

Sodium hippurate, 98% (Hippuric acid, 100 mg/kg; i.p.; five times per week; 10 weeks) promotes renal fibrosis and dysfunction in 5/6 nephrectomized rats[4].
Sodium hippurate, 98% (Hippuric acid, 10 mg/kg; p.o.; daily; 4 weeks) alleviates hyperuricemia in mice by promoting intestinal urate excretion via enhancing ABCG2-mediated transport[5].
Sodium hippurate, 98% (Hippuric acid, 50-150 mg/kg; p.o.; once daily; 7 days) alleviates DSS-induced colitis in male C57BL/6J mice, as shown by reduced clinical activity, improved intestinal barrier integrity, and modulated gut microbiota[6].

Animal Model:Male Sprague Dawley rats (7-week-old, weight not specified); 5/6 nephrectomy model[4]
Dosage:100 mg/kg
Administration: Intraperitoneal injection, five times per week, for 10 weeks
Result:Significantly increased levels of serum creatinine (SCr), blood urea nitrogen (BUN), and HA.
Showed increased tubulointerstitial fibrosis and glomerulosclerosis, with larger COL1A1-, VIM-, and ACTA2-positive areas.
Revealed lower NRF2 levels.
Decreased activities of SOD, CAT, and GSH- Px.
Increased MDA levels in the kidneys, indicating redox imbalance.

IC 50

MMP9; Microbial Metabolite; Human Endogenous Metabolite

HIPPURIC ACID SODIUM SALT Preparation Products And Raw materials

Preparation Products

2-PHENYL-ACETAMIDINEN-PHENYL-1-NAPHTHYLAMINE HYDROBROMIDE, 982-(4-METHOXY-PHENYL)-ACETAMIDINE

HIPPURIC ACID SODIUM SALTSupplier

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Email
market03@meryer.com
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
Alfa Aesar
Tel
400-6106006
Email
saleschina@alfa-asia.com
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Email
Sales-CN@TCIchemicals.com
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HIPPURIC ACID SODIUM SALT(532-94-5)Related Product Information