Methyl 2-(4,6-dichloropyriMidin-5-yl)acetate Chemical Properties

Boiling point:

305.9±37.0 °C(Predicted)

Density 

1.448±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

-4.41±0.50(Predicted)

Appearance

White to off-white Solid

InChI

InChI=1S/C7H6Cl2N2O2/c1-13-5(12)2-4-6(8)10-3-11-7(4)9/h3H,2H2,1H3

InChIKey

ORHWGOUAAWDYFP-UHFFFAOYSA-N

SMILES

C1=NC(Cl)=C(CC(OC)=O)C(Cl)=N1

Methyl 2-(4,6-dichloropyriMidin-5-yl)acetate Usage And Synthesis

Application

4,6-Dichloropyrimidine-5-acetic acid methyl ester is a pharmaceutical intermediate that can be prepared in three steps from diethyl malonate and ethyl bromoacetate as starting materials. It can be used in laboratory research and development processes as well as in chemical production processes.

Synthesis

Methyl 2-(4,6-dichloropyriMidin-5-yl)acetate can be produced through the Fischer esterification of the corresponding carboxylic acid, 2-(4,6-dichloropyrimidin-5-yl)acetic acid.

Methyl 2-(4,6-dichloropyriMidin-5-yl)acetate(171096-33-6)Related Product Information

• Diphenhydramine
• Uracil
• methyl 2-(4-acetamidophenyl)acetate
• Methyl 2-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate
• Ethyl 2-(3-broMoquinolin-6-yl)acetate
• Methyl 2-(4,6-dihydroxypyriMidin-5-yl)acetate
• methyl 2-(2-chloro-4-(6- methylpyrazin-2- yl)phenyl)acetate
• Sulfadiazine
• Pyrimidine