(Z)-2-decanoic acid Chemical Properties

Boiling point:

278.6±9.0 °C(Predicted)

Density 

0.936

storage temp. 

-20°C

solubility 

DMSO : 250 mg/mL (1468.43 mM; Need ultrasonic)

form 

Powder

pka

4.63±0.25(Predicted)

color 

Colorless to light yellow

BRN 

1721990

LogP

3.715 (est)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36

Safety Statements 

26

WGK Germany 

3

(Z)-2-decanoic acid Usage And Synthesis

Uses

cis-2-Decenoic Acid is an organic compound which appears to be functionally and structurally related to the class of short-chain fatty acid signaling molecules such as diffusible signal factor, which act as cell-to-cell communication molecules in bacteria and fungi.

Uses

cis-2-Decenoic acid may be used to study its cytotoxic effect on the human HepG2 cell line. It has also been used to study its synergistic anti-spirochetal effect.

Definition

ChEBI: Cis-2-decenoic acid is a 2-decenoic acid having its double bond in the cis configuration.

Biochem/physiol Actions

cis-2-Decenoic acid is a fatty acid messenger (signaling molecule) produced by Pseudomonas aeruginosa. It possesses anti-biofilm property and converts most of the cells to planktonic (free-swimming) phenotype. cis-2-Decenoic acid retains the susceptibility of the bacteria towards antimicrobial agents. It does not exhibit any toxicity towards human cells and thus, might be used for treating biofilm-associated infections. cis-2-Decenoic acid is considered active even in nano-molar ranges. It mediates the transition of dormant P. aeruginosa and Escherichia coli to their biologically active state without affecting the number of cells. cis-2-Decenoic acid is effective against E. coli and Klebsiella pneumoniae mixed-species biofilms when used along with antimicrobial agents.

(Z)-2-decanoic acid(15790-91-7)Related Product Information

• CIS-2-NONEN-1-OL
• CIS-2-BUTEN-1-OL