6-broMo-8-hydroxy-iMidazo[1,2-a] pyridine hydrochloride Chemical Properties

storage temp. 

Inert atmosphere,Room Temperature

6-broMo-8-hydroxy-iMidazo[1,2-a] pyridine hydrochloride Usage And Synthesis

Synthesis

3-Hydroxy-2-amino-5-bromopyridine (124 mg, 0.65 mmol) was dissolved in ethanol (3 mL), followed by the addition of 50% aqueous chloroacetaldehyde (0.2 mL, 1.3 mmol). The reaction mixture was stirred at 60 °C overnight. After completion of the reaction, the solvent was removed by concentration under reduced pressure and the residue was recrystallized by acetone to afford 6-bromoimidazo[1,2-a]pyridin-8-ol hydrochloride (151 mg, 92% yield).

References

[1] Patent: WO2009/155389, 2009, A1. Location in patent: Page/Page column 88-89
[2] Patent: WO2009/155388, 2009, A1. Location in patent: Page/Page column 98-99

6-broMo-8-hydroxy-iMidazo[1,2-a] pyridine hydrochloride(1379358-48-1)Related Product Information

• 6-Bromoimidazo[1,2-a]pyridin-8-ol
• 6-CHLORO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID
• IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID
• 6-CHLOROIMIDAZO[1,2-A]PYRIDINE
• 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID
• IMidazo[1,2-a]pyridine-8-carboxylic acid, 3-iodo-, ethyl ester