2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-trifluoroMethyluridine Chemical Properties

Density 

1.49±0.1 g/cm3(Predicted)

pka

7.75±0.10(Predicted)

2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-trifluoroMethyluridine Usage And Synthesis

Uses

2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-trifluoromethyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-trifluoroMethyluridine(2072145-74-3)Related Product Information

• 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine
• 2',3',5'-Tri-O-benzoyl-5-difluoromethyluridine
• 2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-Methyluridine
• ThyMidine, α,α,α-trifluoro-, 3',5'-bis(4-Methylbenzoate)