2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-Methyluridine Chemical Properties

Density 

1.39±0.1 g/cm3(Predicted)

pka

9.55±0.10(Predicted)

2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-Methyluridine Usage And Synthesis

Uses

2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-Methyluridine(2072145-23-2)Related Product Information

• 2'-O-Acetyl-5'-O-benzoyl-3'-O-methyl-5-methyluridine
• 5'-O-Toluoyl-2'-O-acetyl-3'-deoxy-3'-fluorouridine
• 2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-trifluoroMethyluridine
• 2'-O-ACETYL-5'-O-BENZOYL-3'-DEOXY-5-METHYLURIDINE
• 2,4(1H,3H)-Pyrimidinedione, 1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-