Basic information Safety Supplier Related

3,4-dihydroxy-α-aminoacetophenone hydrochloride

Basic information Safety Supplier Related

3,4-dihydroxy-α-aminoacetophenone hydrochloride Basic information

Product Name:
3,4-dihydroxy-α-aminoacetophenone hydrochloride
Synonyms:
  • 3,4-dihydroxy-α-aminoacetophenone hydrochloride
  • 2-AMINO-1-(3,4-DIHYDROXYPHENYL)ETHANONE,HCL
  • Norepinephrine EP Impurity B HCl
  • 2-amino-1-(3,4-dihydroxyphenyl)ethanone,hydrochloride
  • Norepinephrine Impurity 1
  • Noradrenaline EP Impurity B HCl
  • Noradrenaline (Norepinephrine) EP Impurity B
  • Norepinephrine Impurity 2(Norepinephrine EP Impurity B)
CAS:
5090-29-9
MF:
C8H10ClNO3
MW:
203.6229
Mol File:
5090-29-9.mol
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3,4-dihydroxy-α-aminoacetophenone hydrochloride Chemical Properties

Melting point:
255 °C
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly, Heated), Water (Very Slightly, Heated)
form 
Solid
color 
Dark Yellow to Dark Brown
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3,4-dihydroxy-α-aminoacetophenone hydrochloride Usage And Synthesis

Uses

Noradrenalone Hydrochloride is an intermediate of Norepinephrine (N674500), an antagonist of dibutyryl cyclic AMP in the regulation of narcosis. Norepinephrine modulates human dendritic cell activation by altering cytokine release.

Preparation

Preparation by demethylation of a-amino-3,4-dimethoxy-acetophenone on heating with 37% hydrochloric acid for 2.5 h at 160–165° under carbon dioxide (85%).

3,4-dihydroxy-α-aminoacetophenone hydrochlorideSupplier

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