Vascular Endothelial Growth Inhibitor Chemical Properties

storage temp. 

-20°C

form 

lyophilized

biological source

human

Safety Information

WGK Germany 

WGK 3

Storage Class

11 - Combustible Solids

Vascular Endothelial Growth Inhibitor Usage And Synthesis

Uses

TL-1A belongs to the TNF superfamily of ligands. It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and colon. TL-1A inhibits endothelial cell proliferation and angiogenesis, and has been shown to induce NFkB activation, caspase activity, and apoptosis in responding cell lines. TL-1A interacts with TNFRSF25/DR3 receptor, but can also bind to a decoy receptor TNFRSF21/DR6. Recombinant human TL-1A is a 22.0 kDa polypeptide of 194 amino acid residues.

Biological Activity

TL-1A belongs to the TNF superfamily of ligands. Recombinant human TL-1A is a 22.0 kDa polypeptide of 194 amino acid residues.

Vascular Endothelial Growth Inhibitor()Related Product Information

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