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Valsartan Impurity 1

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Valsartan Impurity 1 Basic information

Product Name:
Valsartan Impurity 1
Synonyms:
  • N-((2'-(1H-tetrazol-5-yl)
  • N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamide
  • Valsartan Desvalyl Impurity
  • Valsartan Impurity 73
  • Valsartan Desalkyl
  • Pentanamide, N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
CAS:
914465-68-2
MF:
C19H21N5O
MW:
335.4
Mol File:
914465-68-2.mol
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Valsartan Impurity 1 Chemical Properties

Melting point:
191-197°C
Density 
1.186±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Acetonitrilie (Slightly, Heated), Methanol (Slightly)
form 
Solid
pka
4.16±0.10(Predicted)
color 
White to Off-White
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Valsartan Impurity 1 Usage And Synthesis

Uses

N-((2''-(1H-Tetrazol-5-yl)-[1,1''-biphenyl]-4-yl)methyl)pentanamide is an impurity of Valsartan (V095750), an antihypertensive and a nonpeptide angiotensin II AT1-receptor antagonist.

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