TYRPHOSTIN B48
TYRPHOSTIN B48 Basic information
- Product Name:
- TYRPHOSTIN B48
- Synonyms:
-
- AG 494
- A-CYANO-(3,4-DIHYDROXY)-N-PHENYLCINNAMAMIDE
- A-CYANO-(3,4-DIHYDROXY)-N-PHENYLCINNAMIDE
- ALPHA-CYANO-(3,4-DIHYDROXY)-N-PHENYLCINNAMIDE
- (E)-2-CYANO-3-(3,4-DIHYDROXYPHENYL)-N-PHENYL-2-PROPENAMIDE
- N-PHENYL-3,4-DIHYDROXYBENZYLIDENECYANOACETAMIDE
- TYRPHOSTIN AG 494
- TYRPHOSTIN B48
- CAS:
- 139087-53-9
- MF:
- C16H12N2O3
- MW:
- 280.28
- Mol File:
- 139087-53-9.mol
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TYRPHOSTIN B48 Chemical Properties
- Boiling point:
- 586.9±50.0 °C(Predicted)
- Density
- 1.416±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO: soluble
- pka
- 8.80±0.35(Predicted)
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
MSDS
- Language:English Provider:SigmaAldrich
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TYRPHOSTIN B48 Usage And Synthesis
Uses
AG 494 is a potent inhibitor of epidermal growth factor receptor (EGF-R). AG 494 has been found to inhibit cell growth even past the restriction point when receptor activation is no longer necessary; in particular AG 494 causes cells to arrest at late G1 and and during S phase.